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We have previously shown that the pharmacological agents 4-(2-aminoethyl)=benzenesulfonylfluoride hydrochloride (AEBSF) and Na-p-tosyl-L-lysine chloromethylketone (TLCK), inhibitors of trypsin-like serine proteases, prevent the death of trophic factor-deprived PC12 cells and sympathetic neurons. Both AEBSF and TLCK inhibit caspase activation in this model,(More)
BACKGROUND Cost, social acceptability and non-stringent regulations pertaining to smokeless tobacco (SLT) product sales have made people choose and continue using SLT. If disaggregated data on smokeless forms and smoked practices of tobacco are reviewed, the incidence of SLT remains static. There is a strong positive correlation of SLT intake with the(More)
Dengue fever (DF) is the single most important vector-borne viral disease in tropical and subtropical areas worldwide. Globally, estimated 390 million dengue virus infection cases and 100 million incidences of DF occur each year (1). According to the WHO (2), southeast and western Pacific areas carry approximately 75% of global DF infections. This is a(More)
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