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OBJECTIVE To investigate the pathogenesis of proximal diabetic neuropathy (PDN) with nerve and muscle biopsies. BACKGROUND Recent evidence suggests that nerve ischemia secondary to immune-mediated vasculopathy rather than diabetic microangiopathy may be responsible for PDN. METHOD - Fifteen patients with PDN and two diabetic controls underwent nerve and(More)
Ulcerative colitis is an inflammatory condition of unknown aetiology affecting all or part of the rectum and colon. The mainstay of treatment is medical but there are specific indications for surgical intervention. This article reviews the evolution of surgical management and in particular compares outcome from proctocolectomy and pouch surgery. A number of(More)
Ten infertile women were diagnosed as having bilateral or unilateral proximal tubal occlusion in the presence of minimal to mild endometriosis. They were treated with GnRH analogue for 3 months. The aim was to assess the usefulness of therapy in reversing the tubal block. Diagnosis was based on hysterosalpingography, laparoscopy and hysteroscopy. At(More)
Wilson disease is a rare autosomal recessive hereditary disorder of copper metabolism. It is characterized by excessive deposition of copper in the liver, brain, and other tissues due to mutation in the Wilson disease protein (ATP7B) gene which leads to impaired copper metabolism. We report a case of eighteen-year-old male patient, who presented at the(More)
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