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A novel method for detecting neural activity in functional magnetic resonance imaging (fMRI) data is introduced. It is based on canonical correlation analysis (CCA), which is a multivariate extension of the univariate correlation analysis widely used in fMRI. To detect homogeneous regions of activity, the method combines a subspace modeling of the(More)
This article addresses the impact that colored noise, temporal filtering, and temporal detrending have on the fMRI analysis situation. Specifically, it is shown why the detection of event-related designs benefit more from pre-whitening than blocked designs in a colored noise structure. Both theoretical and empirical results are provided. Furthermore, a(More)
This paper presents a method for automatic segmenta-tion of bone from volumetric computed tomography (CT) data. Due to osteoporosis, which degenerates the bone density and hence decreases the intensity of the bone in the CT dataset, it is not possible to use conventional thresh-olding techniques to handle the segmentation. Furthermore we want to use prior(More)
Automatic segmentation of anatomical structures is often performed using model-based non-rigid registration methods. These algorithms work well when the images do not contain any large deviations from the normal anatomy. We have previously used such a method to generate patient specific models of hip bones for surgery simulation. The method that was used,(More)