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Prions are secreted into the oral cavity in sheep with preclinical scrapie.

• Ben Charles Maddison, Helen C Rees, +5 authors Kevin Christopher Gough
• The Journal of infectious diseases
• 2010

A major concern in prion disease transmission is the spread of the disease agent by means of secretions and excretions. We analyzed buccal swab samples obtained from preclinical scrapie-infected… (More)

In vitro amplification of prions from milk in the detection of subclinical infections.

• Kevin Christopher Gough, Claire A Baker, Maged Mohamed Taema, Ben Charles Maddison
• Prion
• 2009

Prions can be amplified by serial protein misfolding cyclic amplification (sPMCA) from the milk of a high proportion of apparently healthy, scrapie exposed sheep with PRNP genotypes not previously… (More)

Differentiating ovine BSE from CH1641 scrapie by serial protein misfolding cyclic amplification.

• Maged Mohamed Taema, Ben Charles Maddison, +6 authors Kevin Christopher Gough
• Molecular biotechnology
• 2012

Whilst ovine BSE displays distinct pathological characteristics to ovine CH1641-like scrapie upon passage in rodents, they have very similar molecular phenotypes. As such, the in vitro… (More)

In vitro amplification of ovine prions from scrapie-infected sheep from Great Britain reveals distinct patterns of propagation

• L. R. Zhu Thorne, Thomas Holder, +6 authors Linda Ann Terry
• BMC veterinary research
• 2012

BACKGROUND Protein misfolding cyclic amplification (PMCA) is a method that facilitates the detection of prions from many sources of transmissible spongiform encephalopathy (TSE). Sheep scrapie… (More)

Retrospective study of Campylobacter infection in a zoological collection.

• Maged Mohamed Taema, James C. Bull, S. Visscher P. M. Knott CORRESPONDENCE Macgregor, Edmund J Flach, Wayne S J Boardman, Andrew Routh
• Applied and environmental microbiology
• 2008

Little is known about the epidemiology of Campylobacter spp. in wild animal populations. However, zoological collections can provide valuable insights. Using records from the Zoological Society of… (More)

Molecular Strain Typing and Environmental Persistence of Ruminant Transmissible Spongiform Encephalopathies

• J. P. Owen, Jonathan Owen, +6 authors Emeli M. Nilsson
• 2012

A novel thermolysin digestion method for the molecular strain-typing of ruminant TSEs has been developed which resulted in the clearance of cellular prion protein (PrP) from healthy sheep or cattle… (More)

Temperature influences the interaction of ruminant PrP (TSE) with soil.

• Ben Charles Maddison, J. P. Owen, Maged Mohamed Taema, George Shaw, Kevin Christopher Gough
• Prion
• 2012

Ovine scrapie and cervid chronic wasting disease can be transmitted in the absence of animal-to-animal contact, and environmental reservoirs of infectivity have been implicated in their spread and… (More)

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