Magdalena Wojan

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Accumulation of fat mass in obesity may result from hypertrophy and/or hyperplasia and is frequently associated with adipose tissue (AT) dysfunction in adults. Here we assessed early alterations in AT biology and function by comprehensive experimental and clinical characterization of 171 AT samples from lean and obese children aged 0 to 18 years. We show an(More)
INTRODUCTION The prevalence of chronic hepatitis C in Germany is about 0.2 - 0.4 %. However, there seems to be regional differences between western and eastern states of the country. Thus, the present study analysed the prevalence of chronic hepatitis C in a cohort of orthopaedic patients in Thuringia. METHODS Tests for antibodies against hepatitis C(More)
Recent studies suggested the persistence of brown adipocytes in adult humans, as opposed to being exclusively present in infancy. In this study, we investigated the presence of brown-like adipocytes in adipose tissue (AT) samples of children and adolescents aged 0 to 18 years and evaluated the association with age, location, and obesity. For this, we(More)
INTRODUCTION In a recent study on hepatitis C prevalence, we identified a high prevalence of elevated liver enzymes, well above 10 %, in orthopaedic surgery patients without evidence for viral hepatitis. We now report in another cohort, that the prevalence is indeed in that range, and that in these patients elevated liver enzymes are likely indicators for(More)
The rare case of an osteoid osteoma in the distal phalanx of the 2nd toe resulting in painful enlargement and hypertrophy of the entire toe in a 12-year-old girl is discussed. The tumour was excised and the oversize of the toe was corrected by exarticulation of the distal phalanx. 18 months postoperatively the patient demonstrates normal function of her(More)
The method of retransfusion of drainage blood as known from the literature was investigated in a prospectiv study regarding effectivness and rate of side effects. 200 patients who underwent total hip and knee arthroplasty were investigated concerning hemoglobin, hematocrit, amount and quality of the retransfused drainage blood, the amount of autologous and(More)
The aneurysmatic bone cyst (ABC) is a benign primary bone tumour. If located in the cervical spine, its expansive growth and destructive behaviour may lead to instability and serious neurological impairment. We report a case of a 16-year-old boy with an aggressive ABC in the 7th cervical vertebra. Computertomographic and magnetic resonance imaging revealed(More)
Dargestellt wird der seltene Fall eines Jungen, der in unserer Klinik mit kongenitaler Patellaluxation und resultierender valgischer Knie- und außenrotierter Fehlstellung des rechten Unterschenkels geboren wurde. Im präsentierten Fall konnte durch Redressionsverfahren mit Gips und Orthesen eine stabile Reposition der Patella erzielt werden. Es fand sich im(More)
Vertebral infection represents 2% to 4% of all cases of osteomyelitis in children. Extension of vertebral osteomyelitis into the vertebral arch is rare; and exclusive pyogenic involvement is exceedingly rare, especially in children. A review of the literature revealed less than 25 combined cases, most of them reported in the beginning of the 20th century(More)
Bis zu 4 % aller Neugeborenen in Mitteleuropa kommen mit einer kongenitalen Hüftdysplasie (KHD) auf die Welt, die somit die häufigste angeborene Erkrankung des Bewegungsapparats ist. Im Rahmen der hier vorgestellten retrospektiven Erhebung wurden die Therapieergebnisse von Neugeborenen mit KHD Typ D, III oder IV nach Graf nachuntersucht, die mit einer(More)