Magdalena Balcerak Jackson

Learn More
1. The patch-clamp technique was used to study channel gating kinetics of the acetylcholine receptor. The agonist carbachol was used at concentrations varying from 0.10 to 20 microM. 2. Data in which many channels were often open at the same time were analysed with the aid of mathematical expressions that relate the stochastic behaviour of a many-channel(More)
  • M B Jackson
  • 1989
The energetics and kinetics of activation of the acetylcholine receptor are evaluated in the context of optimizing rapid synaptic transmission. Physiological needs are used as the basis for estimating optimal values for the closed-to-open channel equilibrium constants of the liganded and unliganded receptor. An estimate is made of the maximum energy that(More)
Elongation by stems of overwintered tubers of Potamogeton pectinatus (L.) is strongly promoted over several days by oxygen-free conditions. Characteristics of the respiration underpinning this unusual response were examined. Anaerobic plants produced ethanol and CO(2) in approximately equimolar amounts, indicating that glycolysis coupled to alcoholic(More)
The requirement for sterility in plant tissue cultures avoidance of dehydration can impose sealing requirements that severely limit the rate of gas exchange in and out of the culture vessel. Conditions within the culture vessel such as the depth of any water cover, the presence of gelling agents, the bulk and porosity of the tissue and the temperature also(More)
This essay concerns the question of how we make genuine epistemic progress through conceptual analysis. Our way into this issue will be through consideration of the paradox of analysis. The paradox challenges us to explain how a given statement can make a substantive contribution to our knowledge, even while it purports merely to make explicit what one's(More)
  • 1