Magda A. El-Sherbeny

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Carboxylic acid imides 1–26 have been synthesized and screened for their antibacterial against gram-positive and gram-negative organisms and their antitumor activity against 60 tumor cell lines taken from nine different organs. Compounds 12, 14, and 16 were the most active and broad-spectrum antibacterial member in this study. Compound 9 showed the most(More)
Twenty-four new compounds were prepared, taking curcumin as a lead, in order to explore their antioxidant and antitumor properties. The capacities of these derivatives to scavenge the 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation (ABTS.+), and to protect human red blood cells (RBCs) from oxidative haemolysis were investigated. In(More)
New series of pyrimido[4,5-b]quinolines and [1,2,4]triazolo[2′,3′:3,4]pyrimido[6,5-b]quinolines have been synthesized. Compounds 4a, 4e, 4f, 4h, 5b, 5d, 6a, 6d, 6e, 8c, 8d, 10c–e, 10h, 11a, 11b, and 12a were tested for in vitro antitumor activity against human breast carcinoma (MCF-7) cell line, where compound 8d was found to be the most active member with(More)
The title compound, C23H22N2O2S, crystallizes with the 4-methyl-benzene-sulfonamide entity oriented towards the center of the bridgehead C atoms with a C-N-S-C torsion angle of -61.3 (2)°. The mol-ecule features an intra-molecular N-H⋯N hydrogen bond. Weak C-H⋯O and C-H⋯π inter-actions aid in forming the three-dimensional supra-molecular structure.
In the title compound, C(14)H(20)N(2)O(2)S, the sulfonamide O atoms lie to one side of the benzene ring and the amino-bicyclo-hepta-nyl to the other side [C(ar)-S-N-C torsion angle = -57.93 (11)°; ar = aromatic]. An intra-molecular N-H⋯N hydrogen bond is formed. In the crystal, a supra-molecular chain is formed along the b axis via N-H⋯O and N-H⋯N hydrogen(More)
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