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BACKGROUND Constituted only by carbon atoms, CNT are hydrophobic and hardly detectable in biological tissues. These properties make biokinetics and toxicology studies more complex. METHODS We propose here a method to investigate the biopersistence of CNT in organism, based on detection of nickel, a metal present in the MWCNT we investigated. RESULTS AND(More)
The mechanisms of toxicity of metal oxide particles towards lung cells are far from being understood. In particular, the relative contribution of intracellular particulate versus solubilized fractions is rarely considered as it is very challenging to assess, especially for low-solubility particles such as cobalt oxide (Co3O4). This study was possible owing(More)
Using zebrafish (Danio rerio) as a case study, we show that the maturity concept of Dynamic Energy Budget (DEB) theory is a useful metric for developmental state. Maturity does not depend on food or temperature contrary to age and to some extent length. We compile the maturity levels for each developmental milestone recorded in staging atlases. The analysis(More)
Titanium dioxide (TiO2) nanoparticles are used in many applications. Due to their small size, easy body penetration and toxicological adverse effects have been suspected. Numerous studies have tried to characterize TiO2 translocation after oral, dermal or respiratory exposure. In this study, we focused on TiO2 nanoparticle biodistribution, clearance and(More)
The toxic action modes of uranium (U) in fish are still scarcely known. U is known to modify the acetylcholinesterase activity in the fish brain. To gain further insight into U neurotoxicity in fish, we examined transcriptional responses in the brain of the zebrafish, Danio rerio, exposed to 15 microg L(-1) and 100 microg L(-1) of waterborne U for 3 and 10(More)
  • Adam-Guillermin C, Pereira S, Della-Vedova C, Hinton T, Garnier-Laplace, Al Kaddissi +56 others
  • 2014
Effects of uranium on crayfish Procambarus clarkii mitochondria and antioxidants responses after chronic exposure: what have we learned ? Ecotoxicology & Environmental Safety, 78: 218-224. Are antioxidant and transcriptional responses useful for discriminating between chemo-and radiotoxicity of uranium in the crayfish Procambarus clarkii? Ecotoxicology and(More)
The effect of chronic exposure to uranium ions (UO(2)(2+)) on sensory tissues including the olfactory and lateral line systems was investigated in zebrafish (Danio rerio) using scanning electron microscopy. The aim of this study was to determine whether exposure to uranium damaged sensory tissues in fish. The fish were exposed to uranium at the(More)
Between January 1982 and June 1985, 2000 patients with either symptoms of cerebrovascular insufficiency (1873) or asymptomatic cervical bruits (127) were studied at the Surgical Department of the University of Brescia (Italy). Of these, 441 presented a mono- or bilateral cervical bruit. The value of the bruit as indicator of an obstructive pathology of the(More)
A retrospective study of 20 patients with somatosensory seizures is undertaken. The cases were obtained from the series of 1000 patient histories from the Division Epilepsy of the Neurological Institute of Montevideo. Several clinical variables are analyzed and especially the etiological factors are studied. A high incidence of surgical treatable causes was(More)
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