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High-k dielectric Al2O3 nanowire and nanoplate field effect sensors for improved pH sensing
- B. Reddy, B. Dorvel, +9 authors R. Bashir
- Materials Science, Medicine
- Biomedical microdevices
- 4 January 2011
Over the last decade, field-effect transistors (FETs) with nanoscale dimensions have emerged as possible label-free biological and chemical sensors capable of highly sensitive detection of various… Expand
“On silico” peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions
- J. Price, Stephanie Tangsombatvisit, +6 authors C. Liu
- Biology, Medicine
- Nature Medicine
- 14 December 2011
We developed a new, silicon-based peptide array for a broad range of biological applications, including potential development as a real-time point-of-care platform. We used photolithography on… Expand
Surface immobilizable chelator for label-free electrical detection of pyrophosphate.
A new pyrophosphate (PPi) chelator was designed for surface-sensitive electrical detection of biomolecular reactions. This article describes the synthesis of the PPi-selective receptor, its surface… Expand
Label-free electrical detection of pyrophosphate generated from DNA polymerase reactions on field-effect devices.
We introduce a label-free approach for sensing polymerase reactions on deoxyribonucleic acid (DNA) using a chelator-modified silicon-on-insulator field-effect transistor (SOI-FET) that exhibits… Expand
16.1 A nanogap transducer array on 32nm CMOS for electrochemical DNA sequencing
- D. Hall, J. Daniels, +8 authors Oguz H. Elibol
- Engineering, Computer Science
- IEEE International Solid-State Circuits…
- 25 February 2016
In this paper, we have demonstrated a highly scalable all-electronic approach towards DNA sequencing using CMOS readout electronics coupled with post-processed nanogap transducers. Expand
Mapping epitopes of U1-70K autoantibodies at single-amino acid resolution
Abstract The mechanisms underlying development of ribonucleoprotein (RNP) autoantibodies are unclear. The U1-70K protein is the predominant target of RNP autoantibodies, and the RNA binding domain… Expand
High-Resolution Analysis of Antibodies to Post-Translational Modifications Using Peptide Nanosensor Microarrays.
Autoantibodies are a hallmark of autoimmune diseases such as lupus and have the potential to be used as biomarkers for diverse diseases, including immunodeficiency, infectious disease, and cancer.… Expand
Fabrication of a CMOS compatible nanopore detector for DNA
Submitted for the MAR10 Meeting of The American Physical Society Fabrication of a CMOS compatible nanopore detector for DNA ASHFAQUE UDDIN, KAVEH MILANINIA, Dept. of Electrical & Computer Eng., UCSB,… Expand
Scalable Nanogap Sensors for Non-Redox Enzyme Assays.
Clinical diagnostic assays that monitor redox enzyme activity are widely used in small, low-cost readout devices for point-of-care monitoring (e.g., a glucometer); however, monitoring non-redox… Expand
Integrated Nanopore Detectors in a Standard Complementary Metal-Oxide-Semiconductor Process