Madi R. Madiyalakan

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Development of sonosensitizers for sonodynamic therapy (SDT) which selectively target abnormal cells can limit undesired side effects in chemotherapeutic applications. Hypocrellin-B (HB) derivatives are low molecular weight compounds which belong to the perylenequinone family of photosensitizing and sonosensitizing compounds. In this study, we investigate(More)
We have used antibody (MAb) specific to hypoglycosylated tumor associated MUC1 as a strategy to induce tumor specific immunity. Xenotypic IgG1 has been previously shown to induce T cell immunity targeting MUC1 in patients. We now describe MUC1 specific IgE to reprogram myeloid cells in the tumor microenvironment and modulate tumor specific immunity. To test(More)
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