Madhusudhan R Sanaka

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OBJECTIVES The effectiveness of colonoscopy in preventing colon cancer depends on adenoma detection and removal. Adequacy of bowel preparation, careful mucosal visualization, and adequate withdrawal time are known to affect adenoma detection rate (ADR). Physician fatigue, which usually increases as the day progresses, might impair ADR. The aim of this study(More)
Serous cystadenomas (SC) of the pancreas are uncommon benign cystic neoplasms that were first differentiated from mucinous cystadenomas in 1978 by Compagno and Oertel [1–3]. SC characteristically have a spongy gross appearance and are composed of innumerable tiny cysts lined by flattened cuboidal or polygonal cells with clear to pale eosinophilic cytoplasm(More)
BACKGROUND ERCP is frequently used in patients with primary sclerosing cholangitis (PSC) for cancer surveillance and treatment of dominant strictures. OBJECTIVE To evaluate the prevalence and risk factors for ERCP-related adverse events in patients with PSC. DESIGN Retrospective analysis of ERCPs performed from 1998 to 2012. SETTING Referral center.(More)
High-resolution, high-definition colonoscopes (HD) with 170° angle of view providing brighter images, sharper resolution, and a 30° wider field of view than conventional colonoscopes (CC) are available. The impact of these innovations on enhancing the detection of clinically important colonic lesions or over detection of clinically insignificant colonic(More)
BACKGROUND Single-balloon enteroscopy (SBE) is a novel endoscopic technique designed to evaluate and treat small-bowel disease. Although there is substantial literature addressing double-balloon enteroscopy and its impact on the diagnosis and management of small-bowel disease, there are limited data available on the clinical utility of SBE. OBJECTIVES To(More)
BACKGROUND & AIMS The Joint Commission on the Accreditation of Healthcare Organizations recommends ventilation monitoring during procedural sedation for gastrointestinal endoscopy. We sought to determine whether intervention, based on a microstream capnography-based ventilation monitoring system that has been shown to function as an early warning system for(More)
BACKGROUND The role of urgent colonoscopy in lower GI bleeding (LGIB) remains controversial. Population-based studies on LGIB outcomes are lacking. OBJECTIVE To investigate the impact of the timing of colonoscopy on outcomes of patients with LGIB. DESIGN Cross-sectional study. SETTING Nationwide Inpatient Sample 2010. PATIENTS International(More)
BACKGROUND Readmission to the hospital within 30 days of discharge (30-day readmission rate) is used as a quality measure. OBJECTIVE To investigate the incidence and factors that contribute to readmissions in patients with acute cholangitis. DESIGN Retrospective cohort study. SETTING Tertiary-care referral center. PATIENTS Retrospective analysis of(More)
OBJECTIVES Ascertaining the benign or malignant nature of biliary strictures may be challenging. Oxidized phospholipids (oxPLs) play an important role in tumor apoptosis and may be elevated in malignant biliary strictures. The objective of the study was to investigate whether oxPLs are enriched in the bile of malignant biliary strictures. METHODS In this(More)
BACKGROUND & AIMS Antegrade and retrograde enteroscopy are useful for evaluating the proximal and distal small bowel, respectively. We compared the diagnostic yield, therapeutic yield, and complications of antegrade and retrograde enteroscopy. METHODS We performed a retrospective review of a prospectively maintained database of patients who underwent(More)