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BACKGROUND Coronary heart disease (CHD) mortality in England fell by approximately 6% every year between 2000 and 2007. However, rates fell differentially between social groups with inequalities actually widening. We sought to describe the extent to which this reduction in CHD mortality was attributable to changes in either levels of risk factors or(More)
BACKGROUND Our aims were to determine the pace of change in cardiovascular risk factors by age, gender and socioeconomic groups from 1994 to 2008, and quantify the magnitude, direction and change in absolute and relative inequalities. METHODS Time trend analysis was used to measure change in absolute and relative inequalities in risk factors by gender and(More)
BACKGROUND Coronary heart disease (CHD) remains a major public health burden, causing 80,000 deaths annually in England and Wales, with major inequalities. However, there are no recent analyses of age-specific socioeconomic trends in mortality. We analysed annual trends in inequalities in age-specific CHD mortality rates in small areas in England, grouped(More)
Objective To determine the effects of community based nurses specialising in Parkinson's disease on health outcomes and healthcare costs. Design Two year randomised controlled trial. Setting 438 general practices in nine randomly selected health authority areas of England. Participants 1859 patients with Parkinson's disease identified by the participating(More)
OBJECTIVE To quantify the contributions of prevention and treatment to the trends in mortality due to coronary heart disease in Scotland. DESIGN Retrospective analysis using IMPACTSEC, a previously validated policy model, to apportion the recent decline in coronary heart disease mortality to changes in major cardiovascular risk factors and to increases in(More)
BACKGROUND Socioeconomic deprivation is associated with increased heart failure (HF) incidence, hospitalization rates, and mortality. However, whether the delivery of survival-enhancing medical therapy is equitable remains uncertain. We examined secular trends in the uptake of key medical therapies (angiotensin-converting enzyme inhibitors or angiotensin(More)
BMJ Open publishes all reviews undertaken for accepted manuscripts. Reviewers are asked to complete a checklist review form are provided with free text boxes to elaborate on their assessment. These free text comments are reproduced below. ARTICLE DETAILS TITLE (PROVISIONAL) The contribution of primary prevention medication and dietary change in coronary(More)
AIMS To estimate the number of coronary heart disease (CHD) deaths potentially preventable in England in 2020 comparing four risk factor change scenarios. METHODS AND RESULTS Using 2007 as baseline, the IMPACTSEC model was extended to estimate the potential number of CHD deaths preventable in England in 2020 by age, gender and Index of Multiple(More)
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