Madeleine Rock

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The spermatic cord was ligated in Charles River adult rats producing viable reversible and non viable damaged testes. Weight of the rats, weight of the testes, weight of the epididymis, sperm motility, sperm concentration and fertility were the different parameters assessed. The results showed that there is a high percentage of subsequent atrophy in the(More)
Intraocular pressure (IOP) was measured in a mixed population of 12,803 apparently healthy employed people. Mean IOP was 13.5 +/- 3.3 mmHg, without sex difference. Frequency distribution demonstrated skewness towards high values. IOP weakly correlated with age (R = 0.06), and older subgroups showed more marked skewness, but further analysis showed this(More)
Two cases of chondrosarcoma involving the proximal femur and the soft tissues are reported. Both patients underwent subtotal femoral resection and quadriceps excision followed by reconstruction with a special prosthesis and arthrodesis of the knee. The tibial stem of the prosthesis was fixed with cement. The advantages of this method are discussed and(More)
1 Morphine-induced mydriasis in mice is antagonized by nalorphine, levallorphan and naloxone in a dose-dependent manner. 2 The relative potency of the three agents is 10:56: 134 respectively, thus being in accordance with other tests of narcotic antagonism. Naloxone has the shortest duration of action. 3 When injected into naive animals, nalorphine (but not(More)
To evaluate the prevalence of hepatitis B virus (HBV) and hepatitis D virus (HDV) infection among intravenous drug addicts (IVDA) in Israel, serum samples were collected from 400 asymptomatic individuals attending a methadone clinic in Tel Aviv. Overall 5.5% were HBsAg positive, 2.4% HBeAg positive, 52% anti-HBc positive and 6.6% were positive for anti-HD.(More)
We have compared IOP values in the two eyes in 13,000 presumably healthy subjects over the age of 40 years. The mean difference in ocular tension between the two eyes was 0.12 mm Hg (higher on the left), which is statistically significant but probably without physiological implications. Individual cases with delta IOP of 3 mm Hg or more were observed more(More)
The metabolic fate of SC-57461, N-methyl-N-[3-[4-(phenylmethyl)-phenoxy]propyl]-beta-alanine, a potent and specific inhibitor of the leukotriene A4 hydrolase, was determined by LC/MS/MS, NMR and GC/MS in male Sprague-Dawley rats. The major metabolites of SC-57461 in rats were the desmethyl metabolite, the hydroxylated metabolite, the N-oxide metabolite, the(More)