Maddalena Brunetti

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BACKGROUND Mirror therapy (MT) was found to improve motor function after stroke, but its neural mechanisms remain unclear, especially in single stroke patients. OBJECTIVES The following imaging study was designed to compare brain activation patterns evoked by the mirror illusion in single stroke patients with normal subjects. METHODS Fifteen normal(More)
Mirror therapy is a therapy to treat patients with pain syndromes or hemiparesis after stroke. However, the underlying neurophysiologic mechanisms are not clearly understood. In order to determine the effect of a mirror-like illusion (MIR) on brain activity using functional near-infrared spectroscopy, 20 healthy right-handed subjects were examined. A MIR(More)
OBJECTIVE To compare lateralized cerebral activations elicited during self-initiated movement mirroring and observation of movements. SUBJECTS A total of 15 right-handed healthy subjects, age range 22-56 years. METHODS Functional imaging study comparing movement mirroring with movement observation, in both hands, in an otherwise identical setting.(More)
BACKGROUND Mirror therapy (MT) was found to improve motor function after stroke. However, there is high variability between patients regarding motor recovery. OBJECTIVES The following pilot study was designed to identify potential factors determining this variability between patients with severe upper limb paresis, receiving MT. METHODS Eleven sub-acute(More)
PURPOSE Mirror therapy can improve motor and sensory functions, but effects of the mirror illusion on primary motor and somatosensory cortex could not be established consistently. METHODS Fifteen right handed healthy volunteers performed or observed a finger-thumb opposition task. Cerebral activations during normal movement (NOR), mirrored movement (MIR)(More)
BACKGROUND Once-weekly dosing of recombinant human erythropoietin (rhEPO) in patients with myelodysplastic syndromes (MDS) has not been investigated thoroughly. We performed a clinical trial to evaluate the effects of this new dosing regimen in patients with MDS who were unresponsive to the conventional three-times-weekly schedule. PATIENTS AND METHODS(More)
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