Madah Khawn-i-Muhammad Mehdi

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The elderly population shows various circadian disturbances, including dampened amplitude of rhythmicity and decreased responsiveness to light. The common poor folate status in the elderly might account for these aging-related circadian disturbances. To test this hypothesis, we investigated whether folate deficiency in mice affects circadian oscillations of(More)
Cone photoreceptor death is a leading cause of blindness in industrialised countries. Despite this, there are few mammalian models available to study cone pathophysiology. The diurnal rodent Arvicanthis possesses a high cone percentage and ease of maintenance. We recently described the effect of ambient light conditions on cyclic disc shedding, and observed(More)
BACKGROUND Retinopathy of prematurity is a serious potentially blinding disease of pre-term infants. There is extensive vascular remodeling and tissue stress, but data concerning alterations in retinal neurons and glia, and long-term functional sequelae are still incomplete. METHODS ROP was induced using the oxygen-induced retinopathy (OIR) mouse model.(More)
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