Macaire Man Saint Yuen

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UNLABELLED White spruce (Picea glauca) is a dominant conifer of the boreal forests of North America, and providing genomics resources for this commercially valuable tree will help improve forest management and conservation efforts. Sequencing and assembling the large and highly repetitive spruce genome though pushes the boundaries of the current technology.(More)
Serial Analysis of Gene Expression (SAGE) has proven to be an important alternative to microarray techniques for global profiling of mRNA populations. We have developed preprocessing methodologies to address problems in analyzing SAGE data due to noise caused by sequencing error, normalization methodologies to account for libraries sampled at different(More)
Currently gene expression data are being produced at a phenomenal rate. The general objective is to try to gain a better understanding of the functions of cellular tissues. In particular, one specific goal is to relate gene expression to cancer diagnosis, prognosis and treatment. However, a key obstacle is that the availability of analysis tools or lack(More)
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