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BACKGROUND During a catheter ablation procedure for selective electrical isolation of pulmonary vein (PV) ostia, the size of these ostia is usually estimated using fluoroscopic angiography. This measurement may be misleading, however, because only the projected supero/inferior ostium diameters can be measured. In this study, we analyzed 3-dimensional(More)
Aim Increasing evidence suggests an important role for hyperactivation of the sympathetic nervous system (SNS) in the clinical phenomena of heart failure with normal LVEF (HFNEF) and hypertension. Moreover, the level of renal sympathetic activation is directly related to the severity of heart failure. Since percutaneous renal denervation (pRDN) has been(More)
OBJECTIVE To determine which clinical variables provide diagnostic information in recognising heart failure in primary care patients with stable chronic obstructive pulmonary disease (COPD) and whether easily available tests provide added diagnostic information. DESIGN Cross sectional diagnostic study. SETTING 51 primary care practices. PARTICIPANTS(More)
We compared ultrasonic duplex scanning and angiography for the localization and classification of arterial stenoses and occlusions in 32 patients. The criteria for the detection of a greater than 50% diameter reducing stenosis was an increase in peak systolic velocity of greater than 100%, loss of reverse flow, and spectral broadening. Duplex studies and(More)
The long-term sequelae of acute deep-vein thrombosis were examined prospectively in a series of 61 patients. The location and extent of the involvement were established by either contrast or isotope phlebography. The mean age of the patients was 47 years, with the duration of follow-up averaging 39 months (range, one to 144 months). Pain and/or swelling was(More)
AIMS To quantify the prevalence of heart failure and left ventricular systolic dysfunction (LVSD) in chronic obstructive pulmonary disease (COPD) patients and vice versa. Further, to discuss diagnostic and therapeutic implications of the co-existence of both syndromes. METHODS AND RESULTS We performed a Medline search from 1966 to March 2005. The reported(More)
AIMS To determine whether peri-coronary epicardial adipose tissue (EAT) is associated with vascular risk factors and coronary atherosclerosis. METHODS AND RESULTS In this study, 573 healthy post-menopausal women underwent a cardiac CT scan to assess coronary calcification. Peri-coronary EAT thickness was measured in the areas of right coronary artery(More)
The physiology of early-diastolic filling comprises ventricular performance and fluid dynamical principles. Elastic recoil and myocardial relaxation rate determine left ventricular early diastolic performance. The integrity of left ventricular synchrony and geometry is essential to maintain the effect of their timely action on early diastolic left(More)
AIMS To compare the ability of different B-type natriuretic peptide (BNP) assays to identify heart failure in stable elderly patients with a diagnosis of chronic obstructive pulmonary disease (COPD). METHODS 200 patients aged >or=65 years with COPD according to their general practitioner and without known heart failure, underwent a diagnostic work-up. The(More)