Maaike de Boer

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Physicians are moving away from routine axillary lymph node dissection (ALND) in clinically node-negative breast cancer. We conducted a systemic review on the safety of this policy. Pubmed and Cochrane library were searched for. Sixty-eight studies were included: studies of clinically node-negative patients in the pre-sentinel node (SN) era; observational(More)
Contrary to the situation in early breast cancer, little is known about the prognostic relevance of the hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) in metastatic breast cancer. The objectives of this study were to present survival estimates and to determine the prognostic impact of breast cancer subtypes based on HR and HER2(More)
Complex video event detection without visual examples is a very challenging issue in multimedia retrieval. We present a state-of-the-art framework for event search without any need of exemplar videos and textual metadata in search corpus. To perform event search given only query words, the core of our framework is a large, pre-built bank of concept(More)
A common approach in content based video information retrieval is to perform automatic shot annotation with semantic labels using pre-trained classifiers. The visual vocabulary of state-of-the-art automatic annotation systems is limited to a few thousand concepts, which creates a semantic gap between the semantic labels and the natural language query. One(More)
Several independent randomized controlled trials are initiated to investigate whether sentinel lymph node biopsy can be safely omitted in clinically node negative breast cancer patients with negative axillary ultrasound findings, who are treated with breast conserving therapy. A consequence of omitting sentinel lymph node biopsy is absence of pathological(More)
Everolimus has important clinical activity in various malignancies, but its use can be complicated by respiratory adverse events. Important everolimus-induced respiratory adverse events are interstitial lung disease (ILD) and infections, either typical or opportunistic. Furthermore, non-everolimus-related respiratory events can occur. Due to the(More)
This paper presents an overview and comparative analysis of our systems designed for TRECVID 2014 [1] multimedia event detection (MED) and recounting (MER) tasks, including all sub-tasks for PreSpecified (PS) event detection, all sub-tasks except 100Ex for Ad-Hoc (AH) event detection, and 010Ex sub-task for both PS and AH event recounting. Multimedia Event(More)
In breast cancer, it has been shown that pN0(i+) and pN1mi have a comparable negative impact on disease-free survival, compared with pN0. However, pN0(i+) is considered to be a heterogeneous group. We determined the effect of metastatic size and microanatomic location within the pN0(i+) group on breast cancer recurrence. We included all Dutch breast cancer(More)