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KIBRA single nucleotide polymorphism (SNP) rs17070145 was identified in a genome-wide association study (GWAS) of memory performance, with some but not all follow-up studies confirming association of its T allele with enhanced memory. This allele was associated with reduced Alzheimer's disease (AD) risk in 1 study, which also found overexpression of KIBRA(More)
  • Ma Li, Dezhong And, Chen
  • 2005
In this paper, we study gradient Ricci expanding soli-tons (X, g) satisfying Rc = cg + D 2 f, where Rc is the Ricci curvature, c < 0 is a constant, and D 2 f is the Hessian of the potential function f on X. We show that for a gradient expanding soliton (X, g) with non-negative Ricci curvature, the scalar curvature R has at least one maximum point on X,(More)
Previously our laboratory has shown that ketamine exposure (24h of clinically relevant anesthesia) causes significant increases in neuronal cell death in perinatal rhesus monkeys. Sensitivity to this ketamine-induced neurotoxicity was observed on gestational days 120-123 (in utero exposure via maternal anesthesia) and on postnatal days (PNDs) 5-6, but not(More)
  • Ma Li, Dezhong And, Chen
  • 2006
Recently, B.Chow and R.S.Hamilton [3] introduced the cross curvature flow on 3-manifolds. In this paper, we analyze two interesting examples for this new flow. One is on a square torus bundle over a circle, and the other is on a S 2 bundle over a circle. We show that the global flow exist in both cases. But on the former the flow diverges at time infinity,(More)
In this paper, we establish two new types of invariant sets for the coupled nonlinear Schrödinger system on R n , and derive two sharp thresholds of blow-up and global existence for its solution. Some analogous results for the nonlinear Schrödinger system posed on the hy-perbolic space H n and on the standard 2-sphere S 2 are also presented. Our arguments(More)
We establish the uniqueness of ground states of some coupled nonlinear Schrodinger systems in the whole space. We firstly use Schwartz symmetrization to obtain the existence of ground states for a more general case. To prove the uniqueness of ground states, we use the radial symmetry of the ground states to transform the systems into an ordinary(More)
Postoperative cognitive dysfunction (POCD) is very common complication of surgery in aged individuals. Accumulated evidence suggests that neuroinflammation may be the underlying cause of POCD. The aim of the present study was to investigate the effects of ulinastatin (UTI) on neuroinflammation and on learning and memory of aged rats after anesthesia and(More)