Małgorzata Pawlikowska

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Phages are called “good viruses” due to their ability to infect and kill pathogenic bacteria. Chlamydia are small, Gram-negative (G−) microbes that can be dangerous to human and animals. In humans, these bacteria are etiological agents of diseases such as psittacosis or respiratory tract diseases, while in animals, the infection may result in enteritis in(More)
RHD (rabbit haemorrhagic disease) virus (RHDV) is the aetiological factor of the haemorrhagic disease of rabbits and is currently present on all continents. RHDV is a small, envelope-free virus containing genetic material in the form of a 7437-nucleotide long RNA strand. Studies indicate that genetic variability of RDHV strains originating from various(More)
The effects of immunisation with Chlamydia psittaci-Gocaltovo strain were examined on the dynamic alterations in lymphocytes T and B and in their subpopulations in the peripheral blood of rabbits; the titer of specific anti-Chlamydia antibodies was also established. The results showed that the examined strain induced alterations in the form of an increased(More)
BACKGROUND Multimerin 1 (MMRN1) is a large, homopolymeric adhesive protein, stored in platelets and endothelium, that when released, binds to activated platelets, endothelial cells and the extracellular matrix. OBJECTIVES The goals of our study were to determine if (i) MMRN1 supports adhesion of resting and/or activated platelets under conditions of blood(More)
The potential oxygen-dependent cidal activity of neutrophilic granulocytes was examined in rabbits immunised with Ch. psittaci-Gocaltovo strain. Tests included a nitrotetrazolium blue (NBT) reduction test and estimation of specific antibody titers. The results obtained indicated that immunization of rabbits with Ch. psittaci-Gocaltovo strain induced(More)
In this paper studies are presented on specific cell-mediated immunity in humans and in laboratory and farm animals upon infection or immunization with bacteria of the genera Chlamydia and Chlamydophila. Such infection or immunization was demonstrated to affect the total number of T lymphocytes, their subpopulation profiles their cytotoxicity, and the(More)
Chlamydiae and Chlamydophilae are bacteria which are very common in the environment, the proof of which can be the recently described "environmental Chlamydiae". The classical Chlamydiae, such as Chlamydia trachomatis and Chlamydophila pneumoniae, posed a threat to human health, causing several diseases, including those with lethal course. In this article(More)
Bacteria from genera Chlamydia (Ch.) and Chlamydophila (Chl.) are very pathogenic and may infect humans and animals. They also may cause latent infection, especially in animals. In this paper we discuss the non-specific and specific cellular and humoral immunity in farm animals, after infection or immunisation with Chlamydia sp. and Chlamydophila sp.(More)
In this study we monitored parameters of non-specific humoral immunity in rabbits immunised with Ch. psittaci-Gocaltovo strain and looked for specific anti-Chlamydia antibodies. The results obtained indicated that the parameters evaluated, including activity of myeloperoxidase and the level and activity of lysozyme, manifested alterations earlier than(More)
Currently, a wide array of plant preparations exerting health-promoting properties are commonly used as feed additives. Among them, Cichorium intybus L. have gained considerable attention as a source of compounds showing prebiotic character. Large body of evidence suggests that products of prebiotic fermentation (short-chain fatty acids) may influence the(More)