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We described course of disease of a 12 year old boy with epilepsy, treated with vigabatrin. Pathological changes in visual field in both eyes are reported after 2 years of treatment.
Vigabatrin (VGB) is a new antiepileptic drug, that acts by the irreversible inhibition of gamma-aminobutyric acid (GABA) aminotransferase. Chronic antiepileptic therapy with VGB is associated with visual field defects and electrophysiological changes.