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Experimental liver metastasis was studied in 4-5 week old athymic nude mice that were injected intrasplenically with a human colorectal tumor cell line (LoVo). A treatment schedule combining 5-fluorouracil and interferon (IFN) was previously shown to inhibit liver metastases. When this treatment was delayed until after splenectomy at 1, 2 and 3 weeks after(More)
Our previous studies showed that interferon (IFN) used in combination with 5-fluorouracil (5-FU) was effective in inhibiting colorectal tumor cell metastases to the liver in nude mice. Furthermore, IFN was also effective in neoadjuvant therapy and allowed the combination treatment (5-FU + IFN) to be delayed for 2-3 weeks following i.s. injections of tumor(More)
Angiosarcomas of the small intestine are rare and present non-specifically. They usually manifest with abdominal discomfort, altered bowel habits, anaemia and gastrointestinal bleeding. Diagnosis is often challenging and occurs at an advanced tumour stage. We describe a case of a terminal ileum angiosarcoma masquerading as an appendiceal abscess, and(More)
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