MJ Reed

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One third of all breast cancers are diagnosed in women aged 70 or over. Older women are a heterogeneous population who are under-represented in clinical trials, and as a result uncertainty can exist as to what represents optimal treatment. This minireview, from an international authorship, summarises the existing evidence surrounding the management of early(More)
BACKGROUND The ACTION trial was initiated to provide evidence from a randomised trial on the effects of chemotherapy in women aged over 70 years where evidence for risk and benefit are lacking. METHODS This was a randomised, phase III clinical trial for high risk, oestrogen receptor (ER) negative/ER weakly positive early breast cancer. The trial planned(More)
Cardiovascular disease is the commonest cause of death in Western society. For this reason much effort has been dedicated to the study of its origins, prevention and treatment. Our group has a specific interest in the analysis of the Electrocardiogram (ECG) in life threatening cardiac arrhythmias and its antecedents, with a view to providing diagnostic(More)
BACKGROUND Older people represent the majority of cancer patients but their specific needs are often ignored in the development of health-related quality of life (HRQOL) instruments. The European Organisation for Research and Treatment of Cancer (EORTC) QLQ-ELD15 was developed to supplement the EORTC's core questionnaire, the QLQ-C30, for measuring HRQOL in(More)
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