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A novel protein kinase which specifically binds single strand DNA was identified in rat liver by chromatography on double strand- and single strand- DNA cellulose. This protein kinase activity was stimulated by cAMP and was inhibited by the heat stable inhibitor, suggesting it was a cAMP-dependent protein kinase. Isoelectric focusing studies confirmed that(More)
As apoptotic pathways are commonly deregulated in breast cancer, exploring how mammary gland cell death is regulated is critical for understanding human disease. We show that primary mammary epithelial cells from protein kinase C delta (PKCδ) -/- mice have a suppressed response to apoptotic agents in vitro. In the mammary gland in vivo, apoptosis is(More)
A 15-week supermarket-based nutrition education program was conducted as part of a larger multiple-strategy community-wide health promotion project. The program consisted of point-of-purchase materials displayed in the supermarkets and was supported by a mass media campaign and promotional activities such as competitions, taste testing and cooking(More)
Glioblastomas are a type of malignant brain tumor and are among the most difficult cancers to treat. One strategy to treat aggressive cancers is the use of drugs that target multiple signaling pathways. MK886 is a drug known to inhibit both 5- lipoxygenase-activating-protein (FLAP) and peroxisome proliferator activated receptor-alpha (PPAR-alpha). The(More)
By examining the relationship of literary form to theological argument in the book of Hebrews, seven theological themes occurring throughout Hebrews are elucidated, each of which is especially prevalent in 11:1-12:2. This smaller section emerges as a theological microcosm of the book as a whole. Upon close inspection, these seven themes can be seen to(More)