MAXIMILIAN STROH

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Mouse cancer models have provided critical insights into tumor biology; however, clinical translation of these findings has been challenging. This perspective posits that factors impacting on successful translation start with limitations in capturing human cancer pathophysiology and end with challenges in generating robust translatable preclinical end(More)
Novae are thermonuclear explosions on a white dwarf surface fueled by mass accreted from a companion star. Current physical models posit that shocked expanding gas from the nova shell can produce x-ray emission, but emission at higher energies has not been widely expected. Here, we report the Fermi Large Area Telescope detection of variable gamma-ray(More)
The Swift X-ray Telescope (XRT) has discovered that flares are quite common in early X-ray afterglows of gamma-ray bursts (GRBs), being observed in roughly 50% of afterglows with prompt follow-up observations. The flares range in fluence from a few per cent to approximately 100% of the fluence of the prompt emission (the GRB). Repetitive flares are seen,(More)
In this note we discuss the extension of the elementary stochastic Itô-integral w.r.t. an optional semimartingale. The paths of an optional semimartingale possess limits from the left and from the right, but may have double jumps. This leads to quite interesting phenomena in integration theory. We find a mathematically tractable domain of general(More)
The editors of HMO PRACTICE asked clinicians and health educators in HMOs across the country to submit reports on their unique, successful patient education programs. The following HMO Innovations testify to the wide range of new technologies, enterprising partnerships, and creative ideas that are shaping health education in HMOs today.
We report on the results of a long term X-ray monitoring campaign of the galactic binary LS I +61 303 performed by the Rossi X-ray Timing Explorer. This dataset consists of 1 ks pointings taken every other day between 2007 August 28 until 2008 February 2. The observations covered six full cycles of the 26.496 day binary period and constitute the largest(More)
Therapeutic drug monitoring (TDM) aims to maintain circulating drug concentrations at a desired level to optimize clinical outcome. The vast majority of marketed drugs do not require TDM, suggesting the clinical benefit of TDM has not been sufficiently demonstrated in most cases. With the continued emergence and prominence of monoclonal antibodies (mAbs) as(More)
We present results from a long-term monitoring campaign on the TeV binary LSI +61 • 303 with VERITAS at energies above 500 GeV, and in the 2-10 keV hard X-ray bands with RXTE and Swift, sampling nine 26.5 day orbital cycles between be variable, with all integrated observations resulting in a detection at the 8.8σ The source was detected during active(More)
Swift-XRT observations of the X-ray emission from gamma ray bursts (GRBs) and during the GRB afterglow have led to many new results during the past two years. One of these exciting results is that ∼1/3 − 1/2 of GRBs contain detectable X-ray flares. The mean fluence of the X-ray flares is ∼10× less than that of the initial prompt emission, but in some cases(More)
We report on the results of a long term X-ray monitoring campaign of the galactic binary LS I +61 303 performed by the Rossi X-ray Timing Explorer. This dataset consists of 1 ks pointings taken every other day between 2007 August 28 until 2008 February 2. The observations covered six full cycles of the 26.496 day binary period and constitute the largest(More)