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Diesel exhaust particles (DEP) contain organic chemicals that contribute to the adverse health effects of inhaled particulate matter. Because DEP induce oxidative stress in the lung and in macrophages, effective antioxidant defenses are required. One type of defense is through the expression of the antioxidant enzyme, heme oxygenase I (HO-1). HO-1 as well(More)
The proinflammatory effects of particulate pollutants, including diesel exhaust particles (DEP), are related to their content of redox cycling chemicals and their ability to generate oxidative stress in the respiratory tract. An antioxidant defense pathway, which involves phase II enzyme expression, protects against the pro-oxidative and proinflammatory(More)
The spatial distribution, movement, and impact of the untreated wastewater outfall from McMurdo Station, Antarctica, were investigated under early austral summer conditions. The benthic environment was examined to determine the distribution of Clostridium perfringens in sediment cores and the intestinal contents of native invertebrates and fish along a(More)
Organic geochemical measurements of the lipid fraction, comparing saturated and aromatic hydrocarbons, fatty acids, alcohols and sterols, have been carried out on six sediments cores collected from the Atlantic shelf, slope and the rise areas to evaluate the cross-shelf transport of the organic carbon. The concentration of most of the organic compound(More)
Vitamin B12 deficiency is common in elderly and vegetarians, but whether screening should be carried out only for these high risk groups or for the entire population, is controversial. Vitamin B12 assays performed on 422 patients in Biochemistry laboratory of tertiary care hospital over a period of 1 year were reviewed. Individuals were considered to be(More)
Muscle tissues of a bottom-dwelling marine fish, white croaker (Genyonemus lineatus), collected near a large wastewater outfall in southern California, USA, were analyzed for long-chain linear alkylbenzenes (LABs). Total LABs (summed concentrations of C11 through C14 isomers) were highest (166-748 ng g-1 wet wt) in individuals collected in the immediate(More)
OBJECTIVE To study the platelet aggregation and lipid profile in offsprings of young ischemic parents. DESIGN Cross sectional. SETTING Hospital based. METHODS 40 adults under 45 years of age with proven CHD and their 50 offsprings comprised the study group. In the control group, 40 age matched adults with normal maximal treadmill test and their 50 off(More)
Spatial distribution of selected contaminants in the surface sediments of Santa Monica Bay (SMB), California was investigated. Sediments were analyzed for DDTs (DDT and metabolites), polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), linear alkylbenzenes (LABs) and coprostanol. Effluent samples from the Hyperion Treatment Plant(More)