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The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia.
- P. Van Vlierberghe, M. van Grotel, +13 authors J. P. P. Meijerink
- Biology, Medicine
- 16 November 2007
T-cell acute lymphoblastic leukemia (T-ALL) is mostly characterized by specific chromosomal abnormalities, some occurring in a mutually exclusive manner that possibly delineate specific T-ALL… Expand
The cryptic chromosomal deletion del(11)(p12p13) as a new activation mechanism of LMO2 in pediatric T-cell acute lymphoblastic leukemia.
To identify new cytogenetic abnormalities associated with leukemogenesis or disease outcome, T-cell acute lymphoblastic leukemia (T-ALL) patient samples were analyzed by means of the… Expand
CD34 expression is associated with poor survival in pediatric T‐cell acute lymphoblastic leukemia
- M. van Grotel, M. M. van den Heuvel-Eibrink, +5 authors J. Meijerink
- Pediatric blood & cancer
- 1 December 2008
Children with T‐lineage acute lymphoblastic leukemia (T‐ALL) have an inferior outcome with combination chemotherapy compared to B‐lineage ALL, and still about 30% of the patients relapse within the… Expand
The outcome of molecular-cytogenetic subgroups in pediatric T-cell acute lymphoblastic leukemia: a retrospective study of patients treated according to DCOG or COALL protocols.
BACKGROUND AND OBJECTIVES Subgroups of T-cell acute lymphoblastic leukemia (T-ALL), defined according to recurrent cytogenetic aberrations, may have different prognoses. The aim of this study was to… Expand
Endovascular versus conventional open repair of acute abdominal aortic aneurysm: feasibility and preliminary results.
- M. V. van Sambeek, L. V. van Dijk, +4 authors H. van Urk
- Journal of endovascular therapy : an official…
- 1 August 2002
PURPOSE To evaluate the feasibility of endovascular treatment of acute abdominal aortic aneurysm (AAA) with commercially prepared bifurcated systems. METHODS From January through July 2001, 22… Expand
Determinants of ototoxicity in 451 platinum-treated Dutch survivors of childhood cancer: A DCOG late-effects study.
- E. Clemens, A. de Vries, +10 authors M. M. van den Heuvel-Eibrink
- European journal of cancer
- 1 December 2016
Platinum-containing chemotherapeutics are efficacious for a variety of pediatric malignancies, nevertheless these drugs can induce ototoxicity. However, ototoxicity data on large cohorts of childhood… Expand
Renin‐induced hypertension in Wilms tumor patients
- M. Maas, K. Cransberg, M. van Grotel, R. Pieters, M. M. van den Heuvel-Eibrink
- Pediatric blood & cancer
- 1 May 2007
Since the report that hypertension associated with Wilms tumor (WT) may be renin‐induced, no larger series than 13 patients have been published. Nevertheless, angiotensin converting enzyme (ACE)… Expand
Hearing loss after platinum treatment is irreversible in noncranial irradiated childhood cancer survivors
- E. Clemens, A. de Vries, +11 authors Marry M van den Heuvel-Eibrink
- Pediatric hematology and oncology
- 17 February 2017
ABSTRACT Cisplatin and carboplatin are effective antineoplastic agents. They are also considered to be potentially highly ototoxic. To date, no long-term follow-up data from well-documented cohorts… Expand
Hypereosinophilic syndrome in children.
- M. van Grotel, M. de Hoog, R. D. de Krijger, H. Beverloo, M. M. van den Heuvel-Eibrink
- Leukemia research
- 1 October 2012
Recently, according to the Hypereosinophilic Diseases Working Group of the International Eosinophil Society, six variants of hypereosinophilic syndrome have been proposed, i.e. (1)… Expand
High relapse rate in children with non-advanced nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL or nodular paragranuloma) treated with chemotherapy only
- M. van Grotel, K. Lam, R. de Man, A. Beishuizen, R. Pieters, M. M. van den Heuvel-Eibrink
- Leukemia & lymphoma
- 1 January 2006
Nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL) is a rare variant of Hodgkin's lymphoma (HL) in children. Since specific immunohistochemical staining has become available, NLPHL can be… Expand