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The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia.
T-cell acute lymphoblastic leukemia (T-ALL) is mostly characterized by specific chromosomal abnormalities, some occurring in a mutually exclusive manner that possibly delineate specific T-ALLExpand
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The cryptic chromosomal deletion del(11)(p12p13) as a new activation mechanism of LMO2 in pediatric T-cell acute lymphoblastic leukemia.
To identify new cytogenetic abnormalities associated with leukemogenesis or disease outcome, T-cell acute lymphoblastic leukemia (T-ALL) patient samples were analyzed by means of theExpand
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CD34 expression is associated with poor survival in pediatric T‐cell acute lymphoblastic leukemia
Children with T‐lineage acute lymphoblastic leukemia (T‐ALL) have an inferior outcome with combination chemotherapy compared to B‐lineage ALL, and still about 30% of the patients relapse within theExpand
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The outcome of molecular-cytogenetic subgroups in pediatric T-cell acute lymphoblastic leukemia: a retrospective study of patients treated according to DCOG or COALL protocols.
BACKGROUND AND OBJECTIVES Subgroups of T-cell acute lymphoblastic leukemia (T-ALL), defined according to recurrent cytogenetic aberrations, may have different prognoses. The aim of this study was toExpand
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Endovascular versus conventional open repair of acute abdominal aortic aneurysm: feasibility and preliminary results.
PURPOSE To evaluate the feasibility of endovascular treatment of acute abdominal aortic aneurysm (AAA) with commercially prepared bifurcated systems. METHODS From January through July 2001, 22Expand
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Determinants of ototoxicity in 451 platinum-treated Dutch survivors of childhood cancer: A DCOG late-effects study.
Platinum-containing chemotherapeutics are efficacious for a variety of pediatric malignancies, nevertheless these drugs can induce ototoxicity. However, ototoxicity data on large cohorts of childhoodExpand
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Renin‐induced hypertension in Wilms tumor patients
Since the report that hypertension associated with Wilms tumor (WT) may be renin‐induced, no larger series than 13 patients have been published. Nevertheless, angiotensin converting enzyme (ACE)Expand
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Hearing loss after platinum treatment is irreversible in noncranial irradiated childhood cancer survivors
ABSTRACT Cisplatin and carboplatin are effective antineoplastic agents. They are also considered to be potentially highly ototoxic. To date, no long-term follow-up data from well-documented cohortsExpand
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Hypereosinophilic syndrome in children.
Recently, according to the Hypereosinophilic Diseases Working Group of the International Eosinophil Society, six variants of hypereosinophilic syndrome have been proposed, i.e. (1)Expand
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High relapse rate in children with non-advanced nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL or nodular paragranuloma) treated with chemotherapy only
Nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL) is a rare variant of Hodgkin's lymphoma (HL) in children. Since specific immunohistochemical staining has become available, NLPHL can beExpand
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