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A carbon dioxide avoidance behavior is integrated with responses to ambient oxygen and food in Caenorhabditis elegans
The results suggest that multiple sensory inputs are coordinated by C. elegans to generate different coherent foraging strategies, which may reflect avoidance of acid pH but appear to define a new sensory response.
Neuronal substrates of complex behaviors in C. elegans.
This work has identified gene products required for nervous system function and elucidated the molecular and neural bases of behaviors in the nematode Caenorhabditis elegans.
Tonic signaling from O2 sensors sets neural circuit activity and behavioral state
This work shows that Caenorhabditis elegans O2-sensing neurons are tonic receptors that continuously signal ambient [O2] to set the animal's behavioral state and highlights how tonic homeostatic signals can generate both transient and enduring behavioral change.
Efficient genome editing in Caenorhabditis elegans by CRISPR-targeted homologous recombination
It is shown that the CRISPR–CRISPR-associated (Cas) system can be adapted for efficient and precise editing of the C. elegans genome.
Neuronal and molecular substrates for optimal foraging in Caenorhabditis elegans
It is suggested that animals integrate information about their nutritional state with ambient oxygen and gustatory stimuli to formulate optimal foraging strategies and that neuroendocrine signaling by TGF-β/DAF-7 and neuronal insulin signaling are necessary for adaptive food-leaving behavior.
Evolution of sex determination in caenorhabditis: unusually high divergence of tra-1 and its functional consequences.
Molecular and functional studies suggest that evolution of sex determination in nematodes is rapid and genetically complex and significant divergence of regulatory regions is indicated.
Decoding a neural circuit controlling global animal state in C. elegans
Neural imaging in unrestrained animals shows that URX and RMG encode O2 concentration rather than behavior, while the activity of downstream interneurons such as AVB and AIY reflect both O2 levels and the behavior being executed.