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MiR-338-3p inhibits epithelial-mesenchymal transition in gastric cancer cells by targeting ZEB2 and MACC1/Met/Akt signaling
MicroRNAs (miRNAs) are involved in the epithelial-mesenchymal transition (EMT) process and are associated with metastasis in gastric cancer (GC). MiR-338-3p has been reported to be aberrantlyExpand
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Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states
Human tryptophanyl-tRNA synthetase (hTrpRS) differs from its bacterial counterpart at several key positions of the catalytic active site and has an extra N-terminal domain, implying possibly aExpand
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Doxorubicin‐Loaded Single Wall Nanotube Thermo‐Sensitive Hydrogel for Gastric Cancer Chemo‐Photothermal Therapy
Single wall carbon nanotube (SWNT) based thermo-sensitive hydrogel (SWNT-GEL) is reported, which provides an injectable drug delivery system as well as a medium for photothermal transduction.Expand
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Requirement of Stat 3 but not Stat 1 Activation for Epidermal Growth Factor Receptor – mediated Cell Growth In Vitro
Stimulation of epidermal growth factor receptor (EGFR) by ligand(s) leads to activation of signaling molecules including Stat1 and Stat3, two members of the signal transducers and activators ofExpand
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IGF1/IGF1R/STAT3 signaling-inducible IFITM2 promotes gastric cancer growth and metastasis.
Interferon-induced transmembrane proteins (IFITMs) are expressed in some types of cancer. However, their precise roles in tumor progression remain unclear. The present study investigated the functionExpand
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Inhibition of SLC1A5 sensitizes colorectal cancer to cetuximab
Cetuximab resistance is a key barrier in treating metastatic colorectal cancer (mCRC). Targeting of metabolic resources import could resensitize drug‐resistant cancer cells to anticancer treatments.Expand
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Cebpα is essential for the embryonic myeloid progenitor and neutrophil maintenance in zebrafish.
  • Yimei Dai, Lu Zhu, +9 authors W. Zhang
  • Medicine, Biology
  • Journal of genetics and genomics = Yi chuan xue…
  • 20 October 2016
In vertebrates, myeloid cells arise from multiple waves of development: the first or embryonic wave of myelopoiesis initiates early from non-hematopoietic stem cell (HSC) precursors and gives rise toExpand
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Impact of liver tumor percutaneous radiofrequency ablation on circulating tumor cells
Radiofrequency ablation has become an increasingly common therapeutic technique for patients with hepatocellular carcinoma or metastatic liver tumors. However, reports on the effect of percutaneousExpand
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XB130 promotes proliferation and invasion of gastric cancer cells
BackgroundXB130 has been reported to be expressed by various types of cells such as thyroid cancer and esophageal cancer cells, and it promotes the proliferation and invasion of thyroid cancer cells.Expand
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Theranostic pH-sensitive nanoparticles for highly efficient targeted delivery of doxorubicin for breast tumor treatment
  • C. Pan, Y. Liu, +4 authors W. Liao
  • Materials Science, Medicine
  • International journal of nanomedicine
  • 27 February 2018
A multifunctional theranostic nanoplatform integrated with environmental responses has been developed rapidly over the past few years as a novel treatment strategy for several solid tumors. WeExpand
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