Development, validation, and evaluation of a pediatric ulcerative colitis activity index: a prospective multicenter study.
- D. Turner, A. Otley, A. Griffiths
- MedicineGastroenterology
- 1 August 2007
The rigorously developed Pediatric Ulcerative Colitis Activity Index is a noninvasive, valid, highly reliable, and responsive index with which to assess disease activity in pediatric ulcerative colitis.
Enteral nutritional therapy for induction of remission in Crohn's disease.
- N. Narula, A. Dhillon, Dongni Zhang, M. Sherlock, M. Tondeur, M. Zachos
- MedicineCochrane Database of Systematic Reviews
- 2018
To evaluate the effectiveness and safety of exclusive EN as primary therapy to induce remission in CD and to examine the importance of formula composition on effectiveness, a systematic review of Randomized controlled trials involving patients with active CD selected studies.
Tumor necrosis factor-alpha antibody for induction of remission in Crohn's disease.
- A. Akobeng, M. Zachos
- MedicineCochrane Database of Systematic Reviews
- 20 October 2003
There is evidence from one randomised controlled trial that suggests that a single intravenous infusion of the monoclonal antibody cA2, infliximab, may be effective for induction of remission in Crohn's disease.
IL-10R Polymorphisms Are Associated with Very-early-onset Ulcerative Colitis
- C. Moran, T. Walters, A. Muise
- Medicine, BiologyInflammatory Bowel Diseases
- 1 January 2013
This study identified the first splice site mutation in IL10RA resulting in infantile-onset IBD and expands the phenotype ofIL10RA polymorphisms to include both severe arthritis and VEO-UC.
Assessment of knowledge in adolescents with inflammatory bowel disease using a novel transition tool
- E. Benchimol, T. Walters, M. Zachos
- MedicineInflammatory Bowel Diseases
- 1 May 2011
The MyHealth Passport for IBD (available freely online) could educate and instill independence in the transitioning adolescent, particularly health services resources.
Gastral Antral Biopsy in the Differentiation of Pediatric Colitides
- P. Kundhal, M. Stormon, M. Zachos, J. Critch, E. Cutz, A. Griffiths
- MedicineAmerican Journal of Gastroenterology
- 1 March 2003
Upper gastrointestinal endoscopy with biopsy is useful in the differentiation of inflammatory bowel disease confined to the colon, particularly when colonoscopic findings are indeterminate.
Pediatric Crohn Disease Activity Index: Responsive to Short-term Change
- P. Kundhal, J. Critch, M. Zachos, A. Otley, D. Stephens, A. Griffiths
- MedicineJournal of Pediatric Gastroenterology and…
- 1 January 2003
The PCDAI is responsive to improvement in disease activity in Crohn disease patients over a short interval and is an appropriate instrument to use in pediatric acute treatment trials.
Enteral nutritional therapy for inducing remission of Crohn's disease.
- M. Zachos, M. Tondeur, A. Griffiths
- MedicineCochrane Database of Systematic Reviews
- 2001
This systematic review aims to provide an update on the existing efficacy data for both corticosteroids versus enteral nutrition and for one form of enteral Nutrition versus another for inducing remission of active Crohn's disease.
Enteral nutritional therapy for induction of remission in Crohn's disease.
- M. Zachos, M. Tondeur, A. Griffiths
- MedicineCochrane Database of Systematic Reviews
- 24 January 2007
A meta-analysis of randomized and quasi-randomized controlled trials involving patients with active Crohn's disease defined by a clinical disease activity index and the importance of formula composition on effectiveness to evaluate the effectiveness of exclusive enteral nutrition as primary therapy to induce remission in Crohn’s disease.
Infliximab-Induced Psoriasis and Psoriasiform Skin Lesions in Pediatric Crohn Disease and a Potential Association With IL-23 Receptor Polymorphisms
- M. Sherlock, T. Walters, A. Griffiths
- MedicineJournal of Pediatric Gastroenterology and…
- 1 May 2013
Adequately powered studies are required to further explore the preliminary findings reported here to determine whether polymorphisms in the IL-23R gene have a role in the pathogenesis of this paradoxical process, which presently remains unexplained.
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