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High-resolution DNA copy number and gene expression analyses distinguish chromophobe renal cell carcinomas and renal oncocytomas
TLDR
The SNP-array analysis failed to detect recurrent small deletions, however, loss of chromosome 2, 10, 13, 17 and 21 is identified as discriminating alteration between chromophobe RCCs and ROs, which can be used for the accurate diagnosis in routine histology.
Molecular pathology of renal oncocytoma: A review
  • M. Yusenko
  • Medicine
    International journal of urology : official…
  • 1 July 2010
TLDR
Supporting data obtained by applying modern microarray‐based technologies are discussed, and it is believed that candidate immunomarkers might not help in the separation of renal oncocytoma from its RCC mimics.
Analysis of differentially expressed mitochondrial proteins in chromophobe renal cell carcinomas and renal oncocytomas by 2-D gel electrophoresis
TLDR
For the first time, mitochondrial proteomes of mitochondria isolated from ROs and chromophobe RCCs as well as from normal kidney tissues are compared by two-dimensional polyacrylamide gel electrophoresis and the proteome profiles were reproducible within the same group of tissues in subsequent experiments.
Oligoarray comparative genomic hybridization of renal cell tumors that developed in patients with acquired cystic renal disease.
TLDR
It is suggested that not only the morphology but also the genetics of renal cell tumors associated with acquired cystic renal disease may differ from those occurring in the general population.
Molecular pathology of chromophobe renal cell carcinoma: A review
  • M. Yusenko
  • Medicine
    International journal of urology : official…
  • 1 July 2010
TLDR
The usefulness of proposed candidate genes selected by the global gene expression analyses in the diagnostic pathology is far below expectations and it is believed that these candidate immunomarkers might not help in the separation of chromophobe RCC, with the exception of CD82.
Identifying CD82 (KAI1) as a marker for human chromophobe renal cell carcinoma
TLDR
The aim was to find an immunohistochemical marker to improve the diagnosis of chromophobe RCC.
Dual role of KRT17: development of papillary renal cell tumor and progression of conventional renal cell carcinoma
TLDR
The continuous expression of KRT17 from emerging fetal kidney tubules and microscopic pre-neoplastic lesions towards papillary renal cell tumors and its neo-expression in aggressive growing conventional renal cell carcinomas reflects the multiple function of K RT17 in kidney cancers with distinct natural history.
First hexagonal close packed high-entropy alloy with outstanding stability under extreme conditions and electrocatalytic activity for methanol oxidation
Abstract High-entropy alloys containing 5 and 6 platinum group metals have been prepared by thermal decomposition of single-source precursors non requiring high temperature or mechanical alloying.
Gene expression profiling of chromophobe renal cell carcinomas and renal oncocytomas by Affymetrix GeneChip using pooled and individual tumours
TLDR
CD82 and S100A1 are identified as valuable markers for chromophobe RCC as well as AQP6 for ROs, however, these genes are expressed at the protein level in other types of RCTs as well albeit at a low frequency and low intensity.
Monensin, a novel potent MYB inhibitor, suppresses proliferation of acute myeloid leukemia and adenoid cystic carcinoma cells.
The master transcriptional regulator MYB is a key oncogenic driver in several human neoplasms, particularly in acute myeloid leukemia (AML) and adenoid cystic carcinoma (ACC). MYB is therefore an
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