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The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer.
Despite remarkable improvements in cancer treatment approaches, breast cancer is still the main cause of cancer-related death in women. Its principal cause is the resistance of the cancer cellsExpand
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CAR-modified T-cell therapy for cancer: an updated review
The use of chimeric antigen receptor (CAR)-modified T cells is a promising approach for cancer immunotherapy. These genetically modified receptors contain an antigen-binding moiety, a hinge region, aExpand
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Phage display as a promising approach for vaccine development
Bacteriophages are specific antagonists to bacterial hosts. These viral entities have attracted growing interest as optimal vaccine delivery vehicles. Phages are well-matched for vaccine design dueExpand
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The use of nanoparticles as a promising therapeutic approach in cancer immunotherapy
Cancer is one of the most important causes of death all over the world, which has not yet been treated efficiently. Although several therapeutic approaches have been used, some side effects such asExpand
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Anti‐angiogenic effects of CD73‐specific siRNA‐loaded nanoparticles in breast cancer‐bearing mice
CD73 facilitates tumor growth by upregulation of the adenosine (immunosuppressive factor) in the tumor microenvironment, however, its precise molecular mechanisms is not precisely understood.Expand
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Immunomodulatory characteristics of mesenchymal stem cells and their role in the treatment of multiple sclerosis.
Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease of central nervous system (CNS). Although the main cause of MS is not clear, studies suggest that MS is an autoimmuneExpand
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The role of oncomirs in the pathogenesis and treatment of breast cancer.
Breast cancer, the most common cancer among women, is a heterogeneous and complex disease, which detail of its precise progression mechanisms is less understood. So, an improved comprehension of theExpand
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Stem cell therapy in Asherman syndrome and thin endometrium: Stem cell- based therapy.
The endometrium is one of the essential components of the uterus. The endometrium of human is a complex and dynamic tissue, which undergoes periods of growth and turn over during any menstrual cycle.Expand
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Effect of Intravenous immunoglobulin on Th1 and Th2 lymphocytes and improvement of pregnancy outcome in recurrent pregnancy loss (RPL).
BACKGROUND Women with elevated natural killer (NK) cell frequency and function during pregnancy, suffer from recurrent pregnancy loss (RPL). In the present study, the possible effect of intravenousExpand
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CRISPR/Cas9 technology as a potent molecular tool for gene therapy
TLDR
In this review, we will discuss CRISPR‐Cas‐based gene editing along with its classifications and mechanism of action. Expand
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