• Publications
  • Influence
Autonomous transposition of the tobacco retrotransposon Tto1 in rice.
TLDR
The results indicate that Tto1 can transpose autonomously through reverse transcription and that the host factors required for transposition are conserved among monocots and dicots, which diverged approximately 200 million years ago. Expand
The serine racemase mRNA is predominantly expressed in rat brain neurons.
TLDR
This is the first study to demonstrate the exact localization of serine racemase mRNA at the cellular or tissue level and suggests that neuron-derived D-serine could modulate neurotransmission via the glycine site of N-methyl-D-aspartate receptors. Expand
Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase.
TLDR
The results indicate the elevated D-serine level following the chronic morphine treatment could at least in part be involved in the activation of NMDA receptors via the glycine site. Expand
Mice lacking d-amino acid oxidase activity display marked attenuation of stereotypy and ataxia induced by MK-801
TLDR
The behavioral effects produced by MK-801 were compared in mutant DAO-/- mice lacking D-amino acid oxidase activity and normal DAO+/+ mice to show marked diminution of stereotypy and ataxia induced byMK-801 compared to normal mice. Expand
Distribution and MK-801-induced expression of serine racemase mRNA in rat brain by real-time quantitative PCR.
TLDR
The present findings suggest that there is a link between the expression of serine racemase mRNA and the activity of the NMDA receptors. Expand
Acute treatment with morphine augments the expression of serine racemase and D-amino acid oxidase mRNAs in rat brain.
TLDR
The present results are the first to suggest an interaction between the expression of the mRNAs for the D-serine-related enzymes and the opioid receptor activation. Expand
Cysteinyl leukotriene receptor antagonists inhibit tumor metastasis by inhibiting capillary permeability.
TLDR
Results show that pranlukast can inhibit tumor cell migration through both the brain and peripheral capillaries, whereas montelukast inhibits tumor cell Migration only in the peripheral capillsaries. Expand
Pharmacological protection from radiation ± cisplatin-induced oral mucositis.
TLDR
It is suggested that Tempol, alone or in combination with D-met, may be a useful and convenient way to prevent the severe oral mucositis that results from head-and-neck cancer therapy. Expand
Effects of MK-801 on the expression of serine racemase and d-amino acid oxidase mRNAs and on the D-serine levels in rat brain.
TLDR
The present findings indicate that increasing the serine racemase mRNA and no changes in the DAO mRNA after the chronic administration could contribute to the elevation of the d-serine level in the forebrain, and that serine Racemase and DAO could play an important role in the regulation of N-methyl-d-aspartate receptors via the d -serine metabolism. Expand
Cognitive Function Related to the Sirh11/Zcchc16 Gene Acquired from an LTR Retrotransposon in Eutherians
TLDR
Gene targeting of mouse SIRH gene 11 / Z inc finger CCHC domain-containing 16 (Sirh11/Zcchc16) causes abnormal behaviors related to cognition, including attention, impulsivity and working memory, suggesting that it has contributed to brain evolution in the three major eutherian lineages, including humans and mice. Expand
...
1
2
3
4
5
...