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The Patient Health Questionnaire, Japanese Version: Validity According to the Mini-International Neuropsychiatric Interview–Plus
To validate the Japanese version of the Patient Health Questionnaire against the Mini-International Neuropsychiatric Interview-Plus in Japan 131 patients in 4 primary care settings and 2 generalExpand
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The anterolateral complex in anterior cruciate ligament deficient knees demonstrate sonographic abnormalities on high-resolution sonography
PurposeThe presence of anterolateral ligament of the knee is still controversial, and some physicians prefer to call this structure anterolateral complex (ALC) to infer plural nature of structuresExpand
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Isolation of New Hexapeptides-JBIR-39 and JBIR-40-from a Marine Sponge-Derived Streptomyces sp. Sp080513SC-24
Streptomyces sp. Sp080513SC-24 was isolated from a marine sponge, Haliclona sp., which is inhabited by diverse Actinobacteria , and then its culture was comprehensively searched for secondaryExpand
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Epigallocatechin gallate decreases the micellar solubility of cholesterol via specific interaction with phosphatidylcholine.
The mechanisms underlying the effect of epigallocatechin gallate (EGCG) on the micellar solubility of cholesterol were examined. EGCG eliminated both cholesterol and phosphatidylcholine (PC) fromExpand
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Synthesis of γ-benzopyranone by TfOH-promoted regioselective cyclization of o-alkynoylphenols.
Regioselective cyclization of o-alkynoylphenols forming γ-benzopyranones has been demonstrated. Trifluoromethanesulfonic acid (TfOH) induced 6-endo cyclization of o-alkynoylphenols without formingExpand
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Conformation-Based Design and Synthesis of Apratoxin A Mimetics Modified at the α,β-Unsaturated Thiazoline Moiety.
We have demonstrated design, synthesis, and biological evaluation of apratoxin A mimetics. In the first generation, the moCys moiety was replaced with seven simple amino acids as their 3D structuresExpand
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A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis
Fibrosis can disrupt tissue structure and integrity and impair organ function. Fibrosis is characterized by abnormal collagen accumulation in the extracellular matrix. Pharmacological inhibition ofExpand
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Total synthesis and conformational analysis of apratoxin C.
Total synthesis of apratoxin C, a cyanobacterial cyclodepsipeptide with highly potent cytotoxicity against some cancer cell lines, was achieved using the apratoxin A synthetic strategy developed byExpand
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Conformationally restricted analog and biotin-labeled probe based on beauveriolide III.
A conformationally restricted oxazoline analog 7 was designed on the basis of a SAR study of beauveriolide III (2) and its analogs reported previously. Conformational analysis by molecular mechanicsExpand
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Potent oxazoline analog of apratoxin C: Synthesis, biological evaluation, and conformational analysis
In this research, the synthesis, biological evaluation, and conformational analysis of an apratoxin C oxazoline analog (3) have been demonstrated. The preparation of synthetic key intermediate 9 wasExpand
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