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Roles of serotonin receptor subtypes for the antinociception of 5-HT in the spinal cord of rats.
The contribution of 5-HT (5-hydroxytryptamine) receptor subtypes to the antinociception produced by intrathecal 5-HT in the formalin test was investigated in rats. Intrathecal 5-HT suppressed both… Expand
A randomized controlled trial of intra-articular prolotherapy versus steroid injection for sacroiliac joint pain.
- W. M. Kim, H. G. Lee, C. Jeong, C. M. Kim, M. Yoon
- Journal of alternative and complementary medicine
- 7 December 2010
OBJECTIVES Controversy exists regarding the efficacy of ligament prolotherapy in alleviating sacroiliac joint pain. The inconsistent success rates reported in previous studies may be attributed to… Expand
Efficacy and tolerability of pregabalin using a flexible, optimized dose schedule in Korean patients with peripheral neuropathic pain: a 10-week, randomized, double-blind, placebo-controlled,…
BACKGROUND Clinical trials from various countries have reported the efficacy of pregabalin for reducing peripheral neuropathic pain. OBJECTIVE This study assessed the efficacy and tolerability of… Expand
The effect of intrathecal gabapentin on pain behavior and hemodynamics on the formalin test in the rat.
UNLABELLED In this study, we examined the effect of intrathecal (i.t.) gabapentin, administered before and after the injection of formalin into the rat hindpaw, on pain behavior and hemodynamics.… Expand
Role of neuronal nitric oxide synthase in the antiallodynic effects of intrathecal EGCG in a neuropathic pain rat model
- Jeong Kyu Choi, Woong Mo Kim, Hyung Gon Lee, Yeo Ok Kim, Myung Ha Yoon
- Medicine, Biology
- Neuroscience Letters
- 21 February 2012
Epigallocatechin-3-gallate (EGCG), the major catechin in green tea, is known to have antioxidant activity against nitric oxide (NO) by scavenging free radicals, chelating metal ions, and inducing… Expand
Fluoroscopically Guided Cervical Interlaminar Epidural Injections Using the Midline Approach: An Analysis of Epidurography Contrast Patterns
- Kwang Su Kim, Sung Sik Shin, Tae Sam Kim, Chang Young Jeong, Myung Ha Yoon, Jeong Il Choi
- Anesthesia and analgesia
- 1 May 2009
BACKGROUND: The purpose of this study was to evaluate epidurography contrast patterns in fluoroscopically guided cervical interlaminar epidural injections using the midline approach. METHODS: All… Expand
The role of alpha-2 adrenoceptor subtype in the antiallodynic effect of intraplantar dexmedetomidine in a rat spinal nerve ligation model
- Hyung Gon Lee, Jeong Il Choi, Yeo Ok Kim, Myung Ha Yoon
- Biology, Medicine
- Neuroscience Letters
- 17 December 2013
The purpose of this study was to examine the effects of intraplantar dexmedetomidine to relieve neuropathic pain and determine the role of peripheral α2-adrenoceptors. Neuropathic pain was induced by… Expand
Spinal gabapentin and antinociception: mechanisms of action.
Spinal gabapentin has been known to show the antinociceptive effect. Although several assumptions have been suggested, mechanisms of action of gabapentin have not been clearly established. The… Expand
Antinociception of Intrathecal Adenosine Receptor Subtype Agonists in Rat Formalin Test
Adenosine has shown antinociceptive action via spinal adenosine receptors. There are four types of adenosine receptors: A1, A2A, A2B, and A3. We characterized the nature of types of adenosine… Expand
Antinociceptive Effect of Memantine and Morphine on Vincristine-induced Peripheral Neuropathy in Rats
Background Vincristine-induced peripheral neuropathy is a major dose limiting side effect and thus effective therapeutic strategy is required. In this study, we investigated the antinociceptive… Expand