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Single dose of rituximab for refractory steroid-dependent nephrotic syndrome in children
TLDR
Treatment with a single dose of rituximab may be effective for refractory SDNS, but its efficacy to prevent relapses was transient in most of the patients. Expand
Differential Pharmacokinetics of Theophylline in Elderly Patients
TLDR
Theophylline has a low therapeutic index because the bronchodilation it produces has a linear relationship with logarithmic increases in serum concentration for the therapeutic range of 5–20 mg/L, so the knowledge of its basic pharmacokinetics and the factors that can alter its clearance is clinically relevant for physicians. Expand
Cerebral salt wasting in subarachnoid hemorrhage rats: model, mechanism, and tool.
TLDR
This study demonstrated for the first time that a rat SAH model exhibited CSW and suggested that the cause of CSW was neither ANP nor BNP. Expand
Experimental model for investigating hyponatremia after subarachnoid hemorrhage in rats.
TLDR
The present results demonstrated for the first time that rats with SAH exhibited excessive natriuresis, a common complication in patients with aneurysmal subarachnoid hemorrhage, and the endovascular puncture model is suitable for investigating hyponatremia that occurs concomitantly with natriureis and diuresis after SAH. Expand
New approach for chronic renal failure model by direct kidney injection of doxorubicin in rats.
TLDR
The results of this study demonstrate that the DXR model using Method C develops CRF within 4 weeks. Expand
Inhibitory effect of hydrocortisone on cerebral salt wasting after subarachnoid hemorrhage in rats.
TLDR
It is concluded that hydrocortisone is a useful drug for the treatment of CSW after SAH because it functioned in a dose-dependent manner to inhibit the increase in sodium excretion and sodium/potassium ratio afterSAH onset. Expand
[Comparative effects of low and medium molecular hydroxyethyl starch (HES) solutions on hemorrhagic shock in rats].
TLDR
The ability of medium-Hes to prolong maintenance of COP better than low-HES is a finding that would be significant in a clinical setting involving preoperative blood management and extreme blood loss. Expand
Is cerebral salt wasting after subarachnoid haemorrhage caused by bleeding
TLDR
The relationship between the amount of bleeding, the intensity of CSW, and the diameter of the middle cerebral artery (MCA) is investigated. Expand
Characterization of cerebral salt wasting after subarachnoid hemorrhage model induced by endovascular puncture.
TLDR
The conclusion is that the spread of bleeding in the subarachnoid space may not cause CSW, and the development of CSW in different SAH models is investigated. Expand
Toxicological study of a glucose-added acetic acid maintenance infusion solution (VEEN 3G Inj.) local irritation test.
TLDR
In clinical use the infusion solution produces extremely slight adverse effects, such as vessel pain and phlebitis on the injection site, which is similar to that of Ringer's solution. Expand