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Stimulation of Osteoblastic Cell Differentiation by Notch
Notch is a transmembrane protein that plays a critical role in the determination of cellular differentiation pathways. Although its importance in the development of mesenchymal tissues has beenExpand
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Suppression of differentiation and proliferation of early chondrogenic cells by Notch
Notch is a transmembrane protein involved in cell fate determination. In the present study, we observed temporally and spatially restricted expression of Notch1 in developing cartilage. Notch1 wasExpand
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PKCγ in Vc and C1/C2 is Involved in Trigeminal Neuropathic Pain
The aim of the present study was to clarify the involvement of protein kinase Cγ (PKCγ) in the facial neuropathic pain following infraorbital nerve injury. We analyzed the change in PKCγ expressionExpand
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Iron as a possible aggravating factor for osteopathy in itai‐itai disease, a disease associated with chronic cadmium intoxication
Itai‐itai disease is thought to be the result of chronic cadmium (Cd) intoxication. We examined 23 autopsy cases of itai‐itai disease and 18 cases of sudden death as controls. Urine and blood samplesExpand
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Molecular Cloning of POEM
Cell adhesion molecules are involved in a number of biological functions, such as cell survival, cell differentiation, tissue repair, and development. A novel molecule, POEM (preosteoblast epidermalExpand
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Changes in the subepithelial mesenchymal cell process meshwork in developing facial prominences in mouse embryos.
We examined temporal and spatial changes in the subepithelial mesenchymal cell process meshwork (CPM) in normally developing medial (MNP) and lateral nasal prominences (LNP) in mouse embryos by lightExpand
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Hematopoietic supportive function of human bone marrow stromal cell lines established by a recombinant SV40-adenovirus vector.
We have previously reported the establishment of a variety of human bone marrow stromal cell lines using a recombinant SV40-adenovirus vector. Using this vector, we obtained more clonal stromalExpand
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P2X3 receptor mediates ectopic mechanical allodynia with inflamed lower lip in mice
Ectopic pain in other orofacial regions develops with local inflammation in separated orofacial structures. However, the basis for the spreading of pain to adjacent orofacial areas after localExpand
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Involvement of peripheral ionotropic glutamate receptors in orofacial thermal hyperalgesia in rats
BackgroundThe purpose of the present study was to elucidate the mechanisms that may underlie the sensitization of trigeminal spinal subnucleus caudalis (Vc) and upper cervical spinal cord (C1-C2)Expand
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Suppressive effects of E3330, a novel quinone derivative, on tumor necrosis factor-α generation from monocytes and macrophages
E3330 {(2E)-3-[5-(2,3-dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonly-2-propenoic acid}, a novel synthesized hepatoprotective compound, has suppressive effects on tumor necrosis factor-α (TNF-α)Expand
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