• Publications
  • Influence
A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts.
NF-kappa B-induced gene expression contributes significantly to the pathogenesis of inflammatory diseases such as arthritis. I kappa B kinase (IKK) is the converging point for the activation ofExpand
  • 142
  • 13
A Selective IKK-2 Inhibitor Blocks NF-κB-dependent Gene Expression in Interleukin-1β-stimulated Synovial Fibroblasts*
NF-κB-induced gene expression contributes significantly to the pathogenesis of inflammatory diseases such as arthritis. IκB kinase (IKK) is the converging point for the activation of NF-κB by a broadExpand
  • 254
  • 10
The role of FDG PET in management of neck metastasis from head-and-neck cancer after definitive radiation treatment.
PURPOSE The role of neck dissection after definitive radiation for head-and-neck cancer is controversial. We select patients for neck dissection based on postradiation therapy (post-RT), computedExpand
  • 181
  • 8
Long-term quality of life for surgical and nonsurgical treatment of head and neck cancer.
OBJECTIVE To compare the long-term, health-related quality-of-life outcomes in patients with advanced head and neck cancer (HNC) treated with surgery and postoperative radiation therapy (SRT) orExpand
  • 101
  • 8
The failure patterns of oral cavity squamous cell carcinoma after intensity-modulated radiotherapy-the university of iowa experience.
PURPOSE Determine the failure patterns of oral cavity squamous cell carcinoma (SCC) treated with intensity-modulated radiotherapy (IMRT). METHODS AND MATERIALS Between May 2001 and July 2005, 55Expand
  • 67
  • 6
  • PDF
Clinical significance of postradiotherapy [18F]-fluorodeoxyglucose positron emission tomography imaging in management of head-and-neck cancer-a long-term outcome report.
PURPOSE To determine the accuracy and prognostic significance of post-treatment [(18)F]-fluorodeoxyglucose positron emission tomography (FDG-PET) in head-and-neck squamous cell carcinoma afterExpand
  • 112
  • 5
Expression of hypoxia-inducible factor-1 alpha and associated proteins in pancreatic ductal adenocarcinoma and their impact on prognosis.
The aim of this study was to assess the significance of expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and associated proteins in pancreatic ductal adenocarcinoma (PDA) and their impactExpand
  • 123
  • 5
Glypican-3 is a biomarker and a therapeutic target of hepatocellular carcinoma.
BACKGROUND The carcinogenesis of hepatocellular carcinoma (HCC) is a multi-factorial, multi-step and complex process. Early diagnosis and effective treatments are of utmost importance. This reviewExpand
  • 37
  • 5
Cell Surface Presenilin-1 Participates in the γ-Secretase-like Proteolysis of Notch*
Presenilin-1 (PS1), a polytopic membrane protein primarily localized to the endoplasmic reticulum, is required for efficient proteolysis of both Notch and β-amyloid precursor protein (APP) withinExpand
  • 249
  • 4
Radiation doses to structures within and adjacent to the larynx are correlated with long-term diet- and speech-related quality of life.
PURPOSE To test the hypothesis that radiation dose to key sites in the upper aerodigestive tract is associated with long-term functional outcome after (chemo)radiotherapy for head-and-neck cancers.Expand
  • 133
  • 4
...
1
2
3
4
5
...