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Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata.
1,4,5,6-Tetrahydro-2-methyl-4-pyrimidinecarboxylic acid (ectoine) is an excellent osmoprotectant. The biosynthetic pathway of ectoine from aspartic beta-semialdehyde (ASA), in Halomonas elongata, wasExpand
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X-ray Structure of β-Carbonic Anhydrase from the Red Alga,Porphyridium purpureum, Reveals a Novel Catalytic Site for CO2 Hydration*
The carbonic anhydrases (CAs) fall into three evolutionarily distinct families designated α-, β-, and γ-CAs based on their primary structure. β-CAs are present in higher plants, algae, andExpand
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Involvement of outer membrane protein TolC, a possible member of the mar-sox regulon, in maintenance and improvement of organic solvent tolerance of Escherichia coli K-12.
Escherichia coli mutants with improved organic solvent tolerance levels showed high levels of outer membrane protein TolC and inner membrane protein AcrA. The TolC level was regulated positively byExpand
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Identification of two myo-inositol transporter genes of Bacillus subtilis.
Among hundreds of mutants constructed systematically by the Japanese groups participating in the functional analysis of the Bacillus subtilis genome project, we found that a mutant with inactivationExpand
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Caveolin Interaction with Protein Kinase C
Caveolar localization of protein kinase C and the regulation of caveolar function by protein kinase C are well known. This study was undertaken to examine whether caveolin subtypes interact withExpand
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Neutral Cysteine Protease Bleomycin Hydrolase Is Essential for the Breakdown of Deiminated Filaggrin into Amino Acids*♦
Filaggrin is a component of the cornified cell envelope and the precursor of free amino acids acting as a natural moisturizing factor in the stratum corneum. Deimination is critical for theExpand
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Phosphorylation by Cyclin-dependent Protein Kinase 5 of the Regulatory Subunit of Retinal cGMP Phosphodiesterase
Retinal cGMP phosphodiesterase (PDE) is regulated by Pγ, the regulatory subunit of PDE, and GTP/Tα, the GTP-bound α subunit of transducin. In the accompanying paper (Matsuura, I., Bondarenko, V. A.,Expand
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Biochemical and genetic characterization of Rbf1p, a putative transcription factor of Candida albicans.
A Candida albicans gene encoding a novel DNA-binding protein that bound to the RPG box of Saccharomyces cerevisiae and the telomeric repeat sequence of C. albicans was previously cloned andExpand
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Kallikrein-related Peptidase 5 Functions in Proteolytic Processing of Profilaggrin in Cultured Human Keratinocytes*
Background: Filaggrin is a skin barrier function-related factor processed from profilaggrin. The identity of human profilaggrin-processing enzymes remains unclear. Results: The protease kallikrein 5Expand
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Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome.
Within the framework of the international project 'The functional analysis of the Bacillus subtilis genome' in Japan and Europe, the gene expression and transcription organization of the gntZ-ywaAExpand
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