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Reversible Suppression of Glutamatergic Neurotransmission of Cerebellar Granule Cells In Vivo by Genetically Manipulated Expression of Tetanus Neurotoxin Light Chain
We developed a novel technique that allowed reversible suppression of glutamatergic neurotransmission in the cerebellar network. We generated two lines of transgenic mice termed Tet and TeNT mice andExpand
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DAP kinase activity is critical for C(2)-ceramide-induced apoptosis in PC12 cells.
Exposure of PC12 cells to C(2)-ceramide results in dose- dependent apoptosis. Here, we investigate the involvement of death-associated protein (DAP) kinase, initially identified as a positiveExpand
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Developmental changes in distribution of death‐associated protein kinase mRNAs
Death‐associated protein kinase (DAP‐kinase) is Ca2+/calmodulin‐dependent serine/threonine kinase that contains ankyrin repeats and the death domain. It has been isolated as a positive mediator ofExpand
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  • Open Access
Unite de regulation de l'expression genetique et utilisation de cette unite
L'invention concerne un outil hautement efficace en matiere de clarification du systeme nerveux cerebral par regulation reversible de l'expression d'une proteine, presentant une activite deExpand