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Nonlinear optical macroscopic assessment of 3-D corneal collagen organization and axial biomechanics.
PURPOSE To characterize and quantify the collagen fiber (lamellar) organization of human corneas in three dimensions by using nonlinear optical high-resolution macroscopy (NLO-HRMac) and to correlateExpand
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Three-dimensional distribution of transverse collagen fibers in the anterior human corneal stroma.
PURPOSE Recent investigations of human corneal structure and biomechanics have shown that stromal collagen fibers (lamellae) are organized into a complex, highly intertwined three-dimensionalExpand
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A Comparative Study of Vertebrate Corneal Structure: The Evolution of a Refractive Lens.
PURPOSE Although corneal curvature plays an important role in determining the refractive power of the vertebrate eye, the mechanisms controlling corneal shape remain largely unknown. To address thisExpand
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Elastic modulus and collagen organization of the rabbit cornea: epithelium to endothelium.
The rabbit is commonly used to evaluate new corneal prosthetics and study corneal wound healing. Knowledge of the stiffness of the rabbit cornea would better inform the design and fabrication ofExpand
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High resolution three-dimensional reconstruction of the collagenous matrix of the human optic nerve head
Glaucoma is the second most common cause of blindness worldwide, leading to irreversible loss of vision. Prior studies indicate that ocular pressure-induced displacement of the lamina cribrosa (LC)Expand
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From nano to macro: studying the hierarchical structure of the corneal extracellular matrix.
In this review, we discuss current methods for studying ocular extracellular matrix (ECM) assembly from the 'nano' to the 'macro' levels of hierarchical organization. Since collagen is the majorExpand
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Magnetoactive liquid crystal elastomer nanocomposites
We present liquid crystal elastomer (LCE) nanocomposites containing superparamagnetic nanoparticles that perform local heat dissipation upon irradiation with electromagnetic fields. A fast localExpand
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Volumetric Reconstruction of the Mouse Meibomian Gland Using High‐Resolution Nonlinear Optical Imaging
Recent studies suggest that mouse meibomian glands (MG) undergo age‐related atrophy that mimics changes seen in age‐related human MG dysfunction (MGD). To better understand the structural/functionalExpand
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Lessons in corneal structure and mechanics to guide the corneal surgeon.
In this issue of Ophthalmology, 2 articles examine the anatomic features that largely determine the corneal tissue response in the performance of 2 evolving corneal transplantation procedures:Expand
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Liquid Crystal Elastomers with Magnetic Actuation
Magneto-active liquid crystal elastomers (LCEs) are accessible by the incorporation of superparamagnetic Fe 3 O 4 nanoparticles into oriented nematic side-chain LCEs and offer a contactlessExpand
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