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The Nigerian health care system: Need for integrating adequate medical intelligence and surveillance systems
  • M. Welcome
  • Medicine, Political Science
    Journal of pharmacy & bioallied sciences
  • 1 March 2011
TLDR
The state of the Nigerian health care system is poorly developed and a system well grounded in routine surveillance and medical intelligence as the backbone of the health sector is necessary, besides adequate management couple with strong leadership principles.
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Gut Microbiota Disorder, Gut Epithelial and Blood–Brain Barrier Dysfunctions in Etiopathogenesis of Dementia: Molecular Mechanisms and Signaling Pathways
  • M. Welcome
  • Biology
    NeuroMolecular Medicine
  • 21 May 2019
TLDR
Very recent data on the molecular mechanisms that link gut microbiota disorder to gut epithelial and blood–brain barrier dysfunctions, underlying the development of dementia are integrated and potential therapeutic options for dementia are highlighted.
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Neuropathophysiology of coronavirus disease 2019: neuroinflammation and blood brain barrier disruption are critical pathophysiological processes that contribute to the clinical symptoms of SARS-CoV-2…
TLDR
The results suggest that downregulation of angiotensin converting enzyme 2 (ACE2) with increased activity of the transmembrane protease serine 2 (TMPRSS2) and cathepsin L in SARS-CoV-2 neuroinvasion may result in upregulation of proinflammatory mediators and reactive species that trigger neuroinflammatory response and blood brain barrier disruption.
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Stress-induced blood brain barrier disruption: molecular mechanisms and signaling pathways.
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Sweet Taste Receptor Signaling Network: Possible Implication for Cognitive Functioning
TLDR
A possible implication of sweet taste receptor signaling in modulating cognitive functioning is proposed, based on increasing evidence about the role of these receptors in the initiation and control of absorption and metabolism, and the pivotal role of metabolic regulation in the central nervous system functioning.
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The Effects of Wet Cupping Therapy on the Blood Levels of Some Heavy Metals: A Pilot Study.
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A MINI-REVIEW OF THE MECHANISMS OF GLUCOSE MEMORY ENHANCEMENT
TLDR
Recent data are reviewed that suggest the mechanisms of glucose enhancement of memory functions and the discovery that glucose memory enhancement effect was comparative with pharmacological agents for memory improvement.
Gastrointestinal Motor Function
TLDR
This chapter aims to identify the course and key milestones in GI motility research and lays down basic concepts and principles of motility of different regions of the gut and their relationship to the maintenance of the functioning of digestion.
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Transcultural Differences in Alcohol Use among Slavic, Arabian And Nigerian Students: A Case Study in Belarus
Effects of dihydropyridine calcium channel blocking drugs on rat brain muscarinic and alpha-adrenergic receptors.
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