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The Alzheimer's disease neuroimaging initiative.
With increasing life expectancy in developed countries, the incidence of Alzheimer's disease (AD) and its socioeconomic impact are growing. Increasing knowledge of the mechanisms of AD facilitatesExpand
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The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods
The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a longitudinal multisite observational study of healthy elders, mild cognitive impairment (MCI), and Alzheimer's disease. Magnetic resonanceExpand
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Cognition and anatomy in three variants of primary progressive aphasia
We performed a comprehensive cognitive, neuroimaging, and genetic study of 31 patients with primary progressive aphasia (PPA), a decline in language functions that remains isolated for at least 2Expand
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Ways toward an early diagnosis in Alzheimer’s disease: The Alzheimer’s Disease Neuroimaging Initiative (ADNI)
With the increasing life expectancy in developed countries, the incidence of Alzheimer's disease (AD) and thus its socioeconomic impact are growing. Increasing knowledge over the last years about theExpand
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Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
Intense multidisciplinary research has provided detailed knowledge of the molecular pathogenesis of Alzheimer disease (AD). This knowledge has been translated into new therapeutic strategies withExpand
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Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease.
Resting-state or intrinsic connectivity network functional magnetic resonance imaging provides a new tool for mapping large-scale neural network function and dysfunction. Recently, we showed thatExpand
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Measurement of hippocampal subfields and age-related changes with high resolution MRI at 4T
Histological studies suggest that hippocampal subfields are differently affected by aging and Alzheimer’s disease (AD). The aims of this study were: (1) To test if hippocampal subfields can beExpand
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Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease
OBJECTIVES To explore volume changes of the entorhinal cortex (ERC) and hippocampus in mild cognitive impairment (MCI) and Alzheimer's disease (AD) compared with normal cognition (NC); to determineExpand
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Patterns of brain atrophy in frontotemporal dementia and semantic dementia
Objective: To identify and compare the patterns of cerebral atrophy associated with two clinical variants of frontotemporal lobar degeneration (FTLD): frontotemporal dementia (FTD) and semanticExpand
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Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease
Background: Neuroimaging in mild cognitive impairment (MCI) and Alzheimer disease (AD) generally shows medial temporal lobe atrophy and diminished glucose metabolism and cerebral blood flow in theExpand
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