• Publications
  • Influence
Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing.
Lung cancer is the leading cause of cancer-related death, with non-small cell lung cancer (NSCLC) being the predominant form of the disease. Most lung cancer is caused by the accumulation of genomicExpand
  • 164
  • 8
Efficient in vitro and in vivo expression of covalently modified plasmid DNA.
The tracking of plasmid DNA (pDNA) movement within cells requires the attachment of labels to the DNA in a manner such that: (a) the pDNA remains intact during the labeling process and (b) the labelsExpand
  • 27
  • 1
MicroRNA Labeling Methods Directly Influence the Accuracy of Expression Profiling Detection
MicroRNA (miRNA) expression profiling is a powerful and commonly used methodology for assessing the relative levels of individual miRNAs in specific tissues. To achieve accurate results using miRNAExpand
  • 6
  • Open Access
Homology requirements for recombination in Escherichia coli ( length dependence / insulin gene / synthetic oligonucleotides / supF miniplasmid
The DNA sequence homology required for recombination in Escherichia coli has been determined by measuring the recombination frequency between insulin DNA in a miniplasmid YrVX and a homologousExpand
  • 1
  • Open Access
Intracellular Localization and Expression of Labeled Plasmid DNA using Label IT Tracker TM Nucleic Acid Labeling Kits
The transfection of plasmid DNA into mammalian cells has become a routine procedure in cellular and molecular biology experiments, yet the mechanism by which the plasmid DNA reaches its nuclearExpand
  • 2
  • Open Access
Improved Cellular Analysis for the Early Detection of Compound-Induced Hepatic Cytotoxicity to Reduce Animal Testing
Most conventional cell-based in vitro assays for the assessment of cell viability and cytotoxicity are disruptive endpoint assays requiring cell lysis. A non-invasive and label-free way toExpand
Direct RNA Labeling for Microarray Profiling using the Label IT
® technology is designed to covalently attach marker molecules to nucleic acids in a simple one-step chemical reaction, allowing sensitive and precise detection of labeled samples. Label IT ®Expand