• Publications
  • Influence
Separation and concentration of schizonts of Plasmodium falciparum by Percoll gradients.
A technique for the separation of schizonts of Plasmodium falciparum is described. The different stages of the asexual cell cycle of the parasite were positioned according to their density in aExpand
  • 107
  • 6
Plasmodium falciparum myosins: transcription and translation during asexual parasite development.
Six myosins genes are now annotated in the Plasmodium falciparum Genome Project. Malaria myosins have been named alphabetically; accordingly, we refer to the two latest additions as Pfmyo-E andExpand
  • 31
  • 3
Ubiquitination dynamics in the early-branching eukaryote Giardia intestinalis
Ubiquitination is a highly dynamic and versatile posttranslational modification that regulates protein function, stability, and interactions. To investigate the roles of ubiquitination in a primitiveExpand
  • 20
  • 3
  • PDF
The multiple myosins of malaria: The smallest malaria myosin, Plasmodium falciparum myosin-B (Pfmyo-B) is expressed in mature schizonts and merozoites
Myosins are motor proteins which, through interaction with filamentous actin, create movement. Multiple myosins have been identified in many of the apicomplexans, however, little is known regardingExpand
  • 14
  • 2
Genetic diversity of Plasmodium falciparum field samples from an isolated Colombian village.
Colombian field isolates of Plasmodium falciparum were analyzed for genetic diversity. Fifty-three samples were collected as thick smears from patients living in Panguí, an isolated area with lowExpand
  • 30
  • 2
Effects of Ca++ depletion on the asexual cell cycle of Plasmodium falciparum.
Ca++ was shown to be indispensable for the normal growth of cultures of Plasmodium falciparum. Inclusion of ethyleneglycolbis (beta-amino-ethylether) N,N'-tetra-acetic acid (EGTA) caused blocking ofExpand
  • 86
  • 1
Identification and expression of the protein ubiquitination system in Giardia intestinalis
Giardia intestinalis is a single-cell eukaryotic microorganism, regarded as one of the earliest divergent eukaryotes and thus an attractive model to study the evolution of regulatory systems. GiardiaExpand
  • 31
  • 1
Stage-specific expression of the calmodulin gene in Plasmodium falciparum.
We studied the synthesis of calmodulin mRNA and of calmodulin during the asexual cell cycle of Plasmodium falciparum. The expression of the gene was low during the early stages of the erythrocyticExpand
  • 16
  • 1
G-Quadruplex ligands: Potent inhibitors of telomerase activity and cell proliferation in Plasmodium falciparum.
Telomeres are DNA and protein structures located at the ends of eukaryotic chromosomes. These structures maintain chromosomal stability by impeding chromosomal ends from being recognized andExpand
  • 19
  • 1
Expression of housekeeping genes during the asexual cell cycle of Plasmodium falciparum
Abstract. In an earlier study, we found that calmodulin displayed an atypical expression for a housekeeping gene during the erythrocytic cycle of Plasmodium falciparum. The expression pattern wasExpand
  • 9
  • 1