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Pharmacokinetics of tablet huperzine A in six volunteers.
- B. Qian, M. Wang, Z. Zhou, K. Chen, R. R. Zhou, G. Chen
- Chemistry, Medicine
- Zhongguo yao li xue bao = Acta pharmacologica…
- 1 September 1995
Hup-A was absorbed rapidly, distributed widely in the body, and eliminated at a moderate rate according to a one-compartment open model with first order absorption. Expand
[Metabolic transformation of schizandrin].
The metabolic transformation of schizandrin, isolated from the kernel of Schizandra chinensis Bill, was studied in vitro with phenobarbital-induced rat liver microsomal fractio containing the NADPH-generating system to determine the metabolic biotransformation in vivo. Expand
Isolation and characterzation of endophytic Huperzine A-producing fungi from Phlegmariurus phlegmaria
Based on special colony morphology, 340 endophytic fungi were isolated from the stems, leaves, and roots of Phlegmariurus phlegmaria, and eight strains were found to have positive results for HupA production and MY311 extract obviously exhibited the highest inhibition activity. Expand
[HPLC analysis of the active ingredients of Forsythia suspensa].
A HPLC method was developed to analyze the active ingredients in Forsythia suspensa to evaluate its quality, and some fruit samples obtained from various sources and the leaf sample made as tea were analyzed by this method. Expand
[Determination of gossypol with high performance liquid chromatography].
Pharmacokinetics of (±)‐, (+)‐, and (−)‐gossypol in humans and dogs
Data from men receiving the compounds orally show that the average peak plasma concentration and the AUC of (+)‐gossypol are significantly greater than those of the (−)‐isomer, indicating higher rates of mass transfer of the−)‐species. Expand
Supercritical fluid chromatography of paclitaxel
The analysis of paclitaxel and related compounds was investigated using supercritical fluid chromatography (SFC). The separation of paclitaxel and five related taxanes was compared on two SFC… Expand
Achiral and chiral analysis of camazepam and metabolites by packed-column supercritical fluid chromatography.
- M. Wang, M. Klee, S. K. Yang
- Chemistry, Medicine
- Journal of chromatography. B, Biomedical…
- 10 March 1995
The results suggest that achiral and chiral packed-column supercritical fluid chromatography gives a shorter analysis time and higher selectivity and efficiency than a chiral and Chiral stationary-phase high-performance liquid chromatography in the analysis of camazepam and its derivatives. Expand
[Studies on the quantitative determination of farrerol in Man-Shan-Hong (Rhododendron dauricum T.)leaves (author's transl)].
[Screening for in vitro metabolites of meisoindigo using RP-HPLC-DAD with gradient elution].
The experimental results show that this method of screening for in vitro metabolites of meisoindigo using RP-HPLC-DAD with gradient elution is characteristic of highly effective separation and specific detection. Expand