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The Genome Sequence of the Malaria Mosquito Anopheles gambiae
Anopheles gambiae is the principal vector of malaria, a disease that afflicts more than 500 million people and causes more than 1 million deaths each year. Tenfold shotgun sequence coverage wasExpand
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The Ecoresponsive Genome of Daphnia pulex
The Daphnia genome reveals a multitude of genes and shows adaptation through gene family expansions. We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200 megabases andExpand
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Mammalian Heart Renewal by Preexisting Cardiomyocytes
Although recent studies have revealed that heart cells are generated in adult mammals, the frequency of generation and the source of new heart cells are not yet known. Some studies suggest a highExpand
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
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MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-β-induced collagen expression via inhibition of E-box repressors
Key features of diabetic nephropathy (DN) include the accumulation of extracellular matrix proteins such as collagen 1-α 1 and -2 (Col1a1 and -2). Transforming growth factor β1 (TGF-β), a keyExpand
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A Comparison of Whole-Genome Shotgun-Derived Mouse Chromosome 16 and the Human Genome
The high degree of similarity between the mouse and human genomes is demonstrated through analysis of the sequence of mouse chromosome 16 (Mmu 16), which was obtained as part of a whole-genomeExpand
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Cycles of chromosome instability are associated with a fragile site and are increased by defects in DNA replication and checkpoint controls in yeast.
We report here that a normal budding yeast chromosome (ChrVII) can undergo remarkable cycles of chromosome instability. The events associated with cycles of instability caused a distinctiveExpand
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FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development.
Light signals perceived by photoreceptors are transduced to negatively regulate COP1, a key repressor of photomorphogenic development. To identify genes involved in light inactivation of COP1, aExpand
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Epidemiologic survey of 196 patients with congenital central hypoventilation syndrome
This study examined the cross‐sectional medical and social characteristics of children diagnosed with congenital central hypoventilation syndrome (CCHS). A detailed questionnaire was mailed to allExpand
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HucMSC‐Exosome Mediated‐Wnt4 Signaling Is Required for Cutaneous Wound Healing
Mesenchymal stem cell‐derived exosomes (MSC‐Ex) play important roles in tissue injury repair, however, the roles of MSC‐Ex in skin damage repair and its mechanisms are largely unknown. Herein, weExpand
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