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An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature
The ISSM unified definition of lifelong and acquired PE represents the first evidence-based definition for these conditions and will enable researchers to design methodologically rigorous studies to improve the understanding of acquired PE. Expand
International Society for Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation.
It is suggested that the prevalence of premature ejaculation is considerably lower than previously thought and that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. Expand
The neurobiological approach to premature ejaculation.
Basic and clinical psychopharmacological studies suggest that premature ejaculation is a not a psychological disturbance but a neurobiological phenomenon. Expand
A multinational population survey of intravaginal ejaculation latency time.
The distribution of the Intravaginal ejaculation latency time (IELT) in all the five countries was positively skewed, with a median IELT of 5.4 minutes but with differences between countries, which was significantly different from each of the other countries. Expand
Effect of SSRI antidepressants on ejaculation: a double-blind, randomized, placebo-controlled study with fluoxetine, fluvoxamine, paroxetine, and sertraline.
In men with lifelong rapid ejaculation, paroxetine delayed ejaculation most strongly, whereas fluvoxamine delayed ejaculations the least, which suggests that ejaculation-delaying side effects of some SSRIs investigated in men with generalized rapid ejaculations may be extrapolated to men with less-rapid ejaculation. Expand
An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine (ISSM) ad hoc committee for the definition of premature ejaculation.
The ISSM definition of lifelong PE represents the first evidence-based definition of PE, and will hopefully lead to the development of new tools and Patient Reported Outcome measures for diagnosing and assessing the efficacy of treatment interventions and encourage ongoing research into the true prevalence of this disorder. Expand
Disorders of orgasm and ejaculation in men.
The recommendations concerning state-of-the-art knowledge of disorders of orgasm and ejaculation represent the opinion of seven experts from seven countries developed in a process over a 2-year period. Expand
Relevance of methodological design for the interpretation of efficacy of drug treatment of premature ejaculation: a systematic review and meta-analysis
At daily treatment, the overall efficacy of paroxetine, clomipramine, sertraline and fluoxetines is comparable, but paroxettine exerts the strongest ejaculation delay. Expand
An Update of the International Society of Sexual Medicine's Guidelines for the Diagnosis and Treatment of Premature Ejaculation (PE)
An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE) and best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients. Expand
Topical eutectic mixture for premature ejaculation (TEMPE): a novel aerosol‐delivery form of lidocaine‐prilocaine for treating premature ejaculation
To evaluate, in a phase II study, the efficacy and safety of a topical eutectic mixture for premature ejaculation (TEMPE), a metered‐dose aerosol spray containing a eutectic mixture of lidocaine andExpand