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The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa
Background Simple and inexpensive non-invasive fibrosis tests are highly needed but have been poorly studied in sub-Saharan Africa. Methods Using liver histology as a gold standard, we developed aExpand
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Modelling in economic evaluation: an unavoidable fact of life.
The role of modelling in economic evaluation is explored by discussing, with examples, the uses of models. The expanded use of pragmatic clinical trials as an alternative to models is discussed. SomeExpand
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Phenotypic or genotypic resistance testing for choosing antiretroviral therapy after treatment failure: a randomized trial
Objective To assess the respective value of phenotype versus genotype versus standard of care for choosing antiretroviral therapy in patients failing protease inhibitor-containing regimens. MethodsExpand
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Postartesunate delayed hemolysis is a predictable event related to the lifesaving effect of artemisinins.
Patients with severe malaria treated with artesunate sometimes experience a delayed hemolytic episode. Artesunate (AS) induces pitting, a splenic process whereby dead parasites are expelled fromExpand
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Extended venous thromboembolism prophylaxis after total hip replacement: a comparison of low-molecular-weight heparin with oral anticoagulant.
BACKGROUND Oral anticoagulants and low-molecular-weight heparin are both recommended for venous thromboembolism prophylaxis after total hip replacement. To date, these regimens have not been comparedExpand
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Identification of hepatitis B virus subgenotype A3 in rural Gabon
An hepatitis B virus (HBV) molecular survey was conducted in five remote villages in the equatorial forest in Gabon, Central Africa. Two hundred seventy out of 311 inhabitants (86.8%) wereExpand
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Macronutrient energy intake and adiposity in non obese prepubertal children aged 5–11 y (the Fleurbaix Laventie Ville Santé Study)
OBJECTIVE: To investigate associations between adiposity indices and food intake in nonobese prepubertal free-living children.SUBJECTS: Five-hundred and one children, 280 boys and 221 girls aged 5–11Expand
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Clinically relevant interpretation of genotype for resistance to abacavir
Objective: To develop a stepwise methodology for the development and validation of clinically relevant genotypic score for resistance to antiretroviral drugs and to apply this approach to theExpand
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Determinants and nature of dietary underreporting in a free-living population: the Fleurbaix Laventie Ville Santé (FLVS) study
OBJECTIVE: To study the determinants and nature of dietary underreporting in a free-living population. DESIGN: Cross-sectional study of nutritional and behavioural characteristics. SUBJECTS: 1030Expand
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Assessing the Severity of Migraine: Development of the MIGSEV Scale
Objectives.—To identify items that serve to assess the severity of migraine with a high level of clinical and psychometric relevance and to combine these into a unitary severity scale.
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