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Designing mobile health technology for bipolar disorder: a field trial of the monarca system
TLDR
The paper discusses three HCI questions related to the design ofpersonal health technologies; how to design for disease awareness and self-treatment, how to ensure adherence to personal health technologies, and the roles of different types of technology platforms. Expand
Cytokines in bipolar disorder vs. healthy control subjects: a systematic review and meta-analysis.
TLDR
A meta-analysis of studies comparing peripheral cytokine concentrations in patients with bipolar disorder with healthy control subjects found some support for peripheral inflammatory alterations in bipolar disorder. Expand
Cytokines in bipolar disorder: a systematic review and meta-analysis.
TLDR
A systemtic review of studies measuring endogenous cytokine concentrations in patients with bipolar disorder and a meta-analysis found some support for immune dysregulation in bipolar disorder. Expand
Salivary cortisol in depressed patients versus control persons: A systematic review and meta-analysis
TLDR
Based on the available studies there is not firm evidence for a difference of salivary cortisol in depressed patients and control persons and salivARY cortisol is unable to discriminate between persons with and without depression. Expand
Measurements of brain-derived neurotrophic factor: Methodological aspects and demographical data
TLDR
Female gender is associated with higher whole blood BDNF concentrations whereas age, thrombocyte count and BDNF Val66Met polymorphism were un-associated, and the BDNF ELISA assay determines whole bloodBDNF accurately and with high reproducibility. Expand
Smartphone data as objective measures of bipolar disorder symptoms
TLDR
The daily electronic self-monitoring Smartphone software "MONARCA" was used by patients with bipolar disorder for 3 consecutive months and self-monitored depressive symptoms correlated significantly with HDRS-17 items score. Expand
Daily electronic self-monitoring in bipolar disorder using smartphones – the MONARCA I trial: a randomized, placebo-controlled, single-blind, parallel group trial
TLDR
The results highlight that electronic self-monitoring, although intuitive and appealing, needs critical consideration and further clarification before it is implemented as a clinical tool. Expand
Behavioral activities collected through smartphones and the association with illness activity in bipolar disorder
TLDR
Objective smartphone data reflect illness severity, discriminates between affective states in BD and may facilitate the cooperation between patient and clinician. Expand
Is there an association between subjective and objective measures of cognitive function in patients with affective disorders?
TLDR
The results suggest that it is not necessarily patients who have cognitive complaints that are most impaired, and that neuropsychological assessment is warranted to elucidate the potential role of cognitive dysfunction in patients’ everyday lives and to inform treatment strategies targeting these difficulties. Expand
Recombinant Human Erythropoietin for Treating Treatment-Resistant Depression: A Double-Blind, Randomized, Placebo-Controlled Phase 2 Trial
TLDR
Exploratory analysis in the complete cohort showed that EPO reduced depression composite at weeks 9 and 14, and highlight EPO as an interesting compound for treatment-resistant depression, which deserves further investigation. Expand
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